Tu Cheng-Quan, Chen Zhi-Da, Yao Xiao-Tao, Jiang Yuan-Jie, Zhang Bi-Fang, Lin Bin
Department of Orthopedic Surgery, The 909 Hospital, School of Medicine, Xiamen University, Zhangzhou 363000, Fujian Province, China.
School of Medicine, Xiamen University, Xiamen 361005, Fujian Province, China.
World J Clin Cases. 2023 Jul 16;11(20):4944-4955. doi: 10.12998/wjcc.v11.i20.4944.
Eosinophilic granuloma (EG) is a proliferative condition that affects the cells of bone tissue. There are no specific clinical signs or imaging manifestations in the early stages of the disease, making it simple to overlook and misdiagnose. Because of the disease's rarity, there is presently no standardized treatment principle. There are few accounts of such occurrences affecting the axis among children. We discovered a case of a child whose EG resulted in atlantoaxial joint dislocation and destruction of the axial bone.
After having pharyngeal discomfort for more than six months without a clear explanation, a 6-year-old boy was brought to our hospital. Following a careful evaluation, the pathology indicated a strong likelihood of an axial EG. Ultimately, we decided to treat the boy with posterior pedicle screw fixation and local steroid injections.
EGs of the upper cervical spine are quite uncommon in children, and they are exceedingly easy to overlook or misdiagnose. Posterior pedicle screw fixation and local steroid injections are effective treatments for patients with axial EGs affecting the atlantoaxial junction.
嗜酸性肉芽肿(EG)是一种影响骨组织细胞的增殖性疾病。该病早期无特异性临床体征或影像学表现,容易被忽视和误诊。由于该病罕见,目前尚无标准化的治疗原则。儿童中发生在脊柱的此类病例报道较少。我们发现了一例儿童嗜酸性肉芽肿导致寰枢关节脱位和脊柱骨破坏的病例。
一名6岁男孩因咽部不适6个多月且原因不明被带到我院。经过仔细评估,病理显示高度怀疑为脊柱嗜酸性肉芽肿。最终,我们决定对该男孩采用后路椎弓根螺钉固定并局部注射类固醇进行治疗。
儿童上颈椎嗜酸性肉芽肿非常罕见,极易被忽视或误诊。后路椎弓根螺钉固定并局部注射类固醇是治疗累及寰枢关节的脊柱嗜酸性肉芽肿患者的有效方法。