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[骨骼肌血管中毛细血管、动脉和静脉压力的血流动力学耦合]

[Hemodynamic coupling of capillary, arterial and venous pressures in skeletal muscle vessels].

作者信息

Dvoretskiĭ D P, Kudriashov Iu A, Savel'ev A K

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1986 Jul;72(7):926-32.

PMID:3758408
Abstract

The dependence of capillary hydrostatic pressure (Pc) on changes of arterial (Pa) and venous (Pv) pressure was determined at different levels of the vascular tone in the m. gastrocnemius, the tone being either reduced with decentralization of the preparation or papaverine, or enhanced with noradrenaline. The Pc and Pv were closely related, the coefficients of the venous pressure transmission onto the capillary level being rather similar (93-97%) within a large range of Pv and vascular tone changes. The conjugation of Pc and Pa was disproportional as revealed in a decrease of the coefficient of arterial pressure transmission onto the capillary pressure, accompanying the Pa growth. This coefficient increased along with a reduction of the muscle arteries tone. The data obtained are regarded from the standpoint of participation of antero- and retrograde hemodynamic effects on capillary pressure and their role in forming the transcapillary fluid exchange in skeletal muscles.

摘要

在不同血管张力水平下,测定了腓肠肌中毛细血管静水压(Pc)对动脉压(Pa)和静脉压(Pv)变化的依赖性。血管张力可通过制备物去神经支配或使用罂粟碱降低,也可通过去甲肾上腺素增强。Pc和Pv密切相关,在Pv和血管张力变化的较大范围内,静脉压传递至毛细血管水平的系数相当相似(93 - 97%)。随着Pa升高,动脉压传递至毛细血管压的系数降低,这表明Pc和Pa的关系不成比例。该系数随肌肉动脉张力降低而增加。从顺行和逆行血流动力学效应参与毛细血管压力形成及其在骨骼肌跨毛细血管液体交换中作用的角度对所得数据进行了分析。

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