Christiana Care Health System, Newark, Delaware, USA.
Texas Tech University Health Sciences Center, Amarillo, USA.
J Investig Med High Impact Case Rep. 2023 Jan-Dec;11:23247096231192923. doi: 10.1177/23247096231192923.
Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder manifesting in myriad of forms and could affect almost any body system or organ. Antiphospholipid syndrome (APLS) is a relatively common scenario in SLE. Both arterial and venous thrombosis is a hallmark feature of APLS. Among others, intracardiac thrombus is a rare and potentially life-threatening presentation. It could occur in any heart chamber whereas the right atrium is the least common location. The treatment is based on anticoagulation preferably with warfarin along with treatment of SLE. We describe a young patient with newly diagnosed SLE with APLS complicated by right atrial thrombus formation. We are, therefore, adding to the scant literature on right atrial thrombi in SLE and increasing awareness of readers of this serious and potentially deadly condition if left unrecognized.
系统性红斑狼疮（SLE）是一种慢性自身免疫性疾病，表现形式多样，几乎可影响任何身体系统或器官。抗磷脂综合征（APLS）是 SLE 中相对常见的情况。动脉和静脉血栓形成是 APLS 的一个显著特征。其中，心内血栓形成是一种罕见且潜在危及生命的表现。它可发生在任何心腔，但右心房是最不常见的部位。治疗基于抗凝，最好使用华法林，同时治疗 SLE。我们描述了一位年轻的患者，新诊断为 SLE 合并 APLS，伴有右心房血栓形成。因此，我们增加了 SLE 中心房血栓形成的文献，提高了读者对这种严重且潜在致命疾病的认识，如果不被识别，可能会导致严重后果。
