Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Department of Anesthesiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
J Clin Sleep Med. 2024 Jan 1;20(1):9-16. doi: 10.5664/jcsm.10770.
Postoperative respiratory complications (PORCs) can occur following supraglottoplasty (SGP) for obstructive sleep apnea. However, there are very limited data on risk factors associated with these complications. This study aims to evaluate the occurrence of PORC in children undergoing SGP and to assess clinical factors and polysomnographic parameters predicting these complications.
A retrospective study was performed in children with laryngomalacia who underwent SGP with preoperative polysomnography.
400 children who underwent SGP met the criteria for entry into the analysis with a total of 416 surgeries with corresponding preoperative polysomnography. The median age (interquartile range) at the time of polysomnography was 0.4 (0.2, 1.5) years. A total of 96 (23.1%) PORCs were noted. Compared with those without complications, children with PORCs had a higher proportion of congenital heart disease ( < .05), higher median obstructive apnea-hypopnea index (obstructive AHI; median 16.0 vs 11.4 events/h; < .01), and lower median oxygen saturation (SpO) ( < .001). The unadjusted odd ratio indicated an increased risk of PORCs in children with congenital heart disease (odds ratio 1.66; < .05) and those with an obstructive AHI > 10 events/h (odds ratio 2.06; < .01). Multiple regression analysis demonstrated that an obstructive AHI > 10 events/h was the only independent risk factor for PORCs ( < .05).
In our cohort of children with laryngomalacia undergoing SGP, those with underlying congenital heart disease, higher obstructive AHI, and lower SpO were more likely to develop PORCs. Only children with an obstructive AHI > 10 events/h were at significantly increased risk for PORCs following SGP. Preoperative polysomnography is useful in preoperative planning in children undergoing SGP.
Kanavitoon S, Ngamprasertwong P, Gurbani N, et al. Polysomnographic parameters and clinical risk factors predicting postoperative respiratory complications in children undergoing supraglottoplasty. . 2024;20(1):9-16.
悬雍垂腭咽成形术(SGP)治疗阻塞性睡眠呼吸暂停后可能会发生术后呼吸系统并发症(PORC)。然而,与这些并发症相关的危险因素数据非常有限。本研究旨在评估 SGP 术后儿童 PORC 的发生情况,并评估预测这些并发症的临床因素和多导睡眠图参数。
对接受术前多导睡眠图检查的喉软化症患儿进行 SGP 后,进行回顾性研究。
400 名接受 SGP 的儿童符合纳入分析标准,共进行了 416 例手术,相应地进行了术前多导睡眠图检查。多导睡眠图检查时的中位年龄(四分位间距)为 0.4(0.2,1.5)岁。共发现 96 例(23.1%)PORC。与无并发症的患儿相比,PORC 患儿先天性心脏病的比例更高(<0.05),中位阻塞性呼吸暂停低通气指数(obstructive AHI;中位数 16.0 比 11.4 次/小时;<0.01)更高,中位血氧饱和度(SpO)更低(<0.001)。未调整的优势比表明,患有先天性心脏病的患儿(比值比 1.66;<0.05)和阻塞性 AHI > 10 次/小时的患儿(比值比 2.06;<0.01)发生 PORC 的风险增加。多元回归分析表明,阻塞性 AHI > 10 次/小时是 PORC 的唯一独立危险因素(<0.05)。
在我们的喉软化症患儿 SGP 队列中,患有基础先天性心脏病、更高的阻塞性 AHI 和更低的 SpO 的患儿更有可能发生 PORC。只有阻塞性 AHI > 10 次/小时的患儿在 SGP 后发生 PORC 的风险显著增加。术前多导睡眠图在 SGP 患儿的术前计划中很有用。
Kanavitoon S, Ngamprasertwong P, Gurbani N, et al. 多导睡眠图参数和临床危险因素预测行悬雍垂腭咽成形术儿童的术后呼吸系统并发症。2024;20(1):9-16。