Department of Orthopedics, University of California, San Diego, CA.
Division of Orthopedics & Scoliosis, Rady Children's Hospital, San Diego, CA.
Spine (Phila Pa 1976). 2024 Jan 1;49(1):15-21. doi: 10.1097/BRS.0000000000004799. Epub 2023 Aug 15.
Observational case control.
The objective of this study was to evaluate the prevalence of opioid use two years after surgical correction of adolescent idiopathic scoliosis (AIS) and its association with preoperative mental health.
Studies of opiate use have reported that up to 80% of users began their addiction with misuse of prescription opioids. Identifying opioid use and those at risk in the AIS population is critical for optimal outcomes.
A query of a multicenter prospective AIS surgical fusion registry was performed to identify patients of all curve types with responses to question 11 on the Scoliosis Research Society-22 questionnaire at two years postoperative. Question 11 asks about pain medication usage for the patient's back with five specific responses: narcotics daily, narcotics weekly or less, non-narcotics daily, non-narcotics weekly/less, or none. Ordinal regression was used to evaluate the association between preoperative Scoliosis Research Society-22 Mental Health (MH) domain scores and two-year postoperative pain medication usage.
A total of 2595 patients who underwent surgery from 2002 to 2019 met inclusion. The average primary curve was 56±12°, average age 14.7±3 years, and 81.5% were female. Forty (1.5%) patients reported utilizing opioids two years after surgery, and a significant difference in preoperative MH scores was observed. Patients taking daily opioids postoperatively had the lowest median preoperative MH score (3.75), followed by non-narcotic group (4), and no medication (4.2, P <0.001). Three patients reporting opioid use postoperatively reported preoperative usage. The rate of two-year postoperative medication use based on the year of surgery demonstrated a small linear decrease in opioid use over time, with a slight increase in nonopioid daily use.
Less than 2% of patients reported taking opioids for back pain two years after surgical correction of AIS. A lower MH score before surgery may place a patient at increased risk for opioid use two years after surgery. An analysis of the year of surgery suggests that changes in prescription practices over time may be occurring.
观察性病例对照研究。
本研究旨在评估青少年特发性脊柱侧凸(AIS)手术后两年阿片类药物使用的流行率及其与术前心理健康的关系。
阿片类药物使用研究报告称,高达 80%的使用者最初是通过滥用处方阿片类药物开始成瘾的。在 AIS 人群中识别阿片类药物的使用情况和高危人群对于获得最佳结果至关重要。
对一个多中心前瞻性 AIS 手术融合登记处进行查询,以确定所有曲线类型的患者在术后两年时对 Scoliosis Research Society-22 问卷的问题 11 做出了回答。问题 11 询问患者背部疼痛药物的使用情况,有五个具体回答:每天使用麻醉剂、每周或更少使用麻醉剂、每天使用非麻醉剂、每周或更少使用非麻醉剂、或无。采用有序回归评估术前 Scoliosis Research Society-22 心理健康(MH)域评分与两年后术后疼痛药物使用之间的关联。
共有 2595 名 2002 年至 2019 年间接受手术的患者符合纳入标准。平均主曲线为 56±12°,平均年龄为 14.7±3 岁,81.5%为女性。术后两年有 40 名(1.5%)患者报告使用阿片类药物,术前 MH 评分存在显著差异。术后每天使用阿片类药物的患者术前 MH 评分最低(3.75),其次是非麻醉组(4)和无药物组(4.2,P<0.001)。术后报告使用阿片类药物的 3 名患者术前有使用史。基于手术年份的两年后药物使用率显示,随着时间的推移,阿片类药物的使用呈线性下降趋势,而非阿片类药物的每日使用量略有增加。
不到 2%的患者报告在 AIS 手术后两年因背部疼痛服用阿片类药物。手术前 MH 评分较低可能使患者在手术后两年内使用阿片类药物的风险增加。对手术年份的分析表明,随着时间的推移,处方实践可能发生变化。
4 级。