利用带有突起的取向纳米纤维和半乳糖凝集素-1 涂层促进神经突生长和神经干细胞迁移。
Promoting neurite outgrowth and neural stem cell migration using aligned nanofibers decorated with protrusions and galectin-1 coating.
机构信息
Shandong Key Laboratory of Medical and Health Textile Materials, Collaborative Innovation Center for Eco-textiles of Shandong Province and the Ministry of Education, College of Textile & Clothing, Qingdao University, Qingdao 266071, China.
Qingdao Medical College, Qingdao University, Qingdao 266071, China.
出版信息
Chem Commun (Camb). 2023 Sep 7;59(72):10753-10756. doi: 10.1039/d3cc02869k.
Biomaterials integrated with both topological cues and biological modifications are urgently needed in regenerative medicine. Here, aligned nanofibrous scaffolds decorated with nanoscale SiO protrusions and galectin-1 coating are reported. Prospects in neurite outgrowth and neural stem cell migration are discussed for suitable use in neural tissue engineering.
在再生医学中，迫切需要将拓扑线索和生物修饰结合在一起的生物材料。本文报道了一种具有纳米级 SiO2 突起和半乳糖凝集素-1 涂层的取向纳米纤维支架。讨论了其在神经突生长和神经干细胞迁移方面的应用前景，以期在神经组织工程中得到合适的应用。
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