Moran H, Hanna D B, Ansell B M, Hall M, Engler C
Ann Rheum Dis. 1979 Apr;38(2):152-4. doi: 10.1136/ard.38.2.152.
Naproxen at 10 mg per kg body weight was compared with aspirin at 80 mg per kg body weight in children suffering from juvenile chronic polyarthritis. It was found to be as effective as aspirin, with certainly no more and possibly fewer gastrointestinal side effects. A long-term tolerance study up to 12 months confirmed that naproxed was a satisfactory nonsteroidal anti-inflammatory drug in the management of various types of juvenile chronic arthritis.
在患有青少年慢性多关节炎的儿童中,对每千克体重服用10毫克萘普生与每千克体重服用80毫克阿司匹林进行了比较。结果发现它与阿司匹林效果相同,胃肠道副作用肯定不会更多,甚至可能更少。一项长达12个月的长期耐受性研究证实,萘普生在治疗各种类型的青少年慢性关节炎方面是一种令人满意的非甾体抗炎药。