Astbury J, Orgill A A, Bajuk B, Yu V Y
Dev Med Child Neurol. 1986 Aug;28(4):472-9. doi: 10.1111/j.1469-8749.1986.tb14285.x.
The pattern of growth of 235 very low-birthweight children, whose weights were appropriate for gestational age, was characterised by a significant decline in weight, length and head circumference from birth to discharge from hospital, followed by partial recovery in all three measures of growth by two years corrected age. 29 per cent of the children were below the 10th percentile for weight at two years, and this group had a significantly higher incidence of major disabilities, poorer muscular development, more hypotonia and lowered performance on the psychomotor index of the Bayley Scales of Infant Development than their heavier peers. These children's mothers more often perceived them as actively disliking close physical contact, and they were reported by their mothers to have had more infections, minor surgery and chronic otitis media. Taken together, the suboptimal weight-gain, delayed gross motor development and increased maternal perceptions of 'sickliness' and lack of 'cuddliness' in these children are reminiscent of non-organic failure to thrive.
235名出生体重极低但出生体重与胎龄相符的儿童的生长模式特点为，从出生到出院体重、身长和头围显著下降，到矫正年龄两岁时这三项生长指标部分恢复。29%的儿童在两岁时体重低于第10百分位，与体重较重的同龄人相比，该组儿童严重残疾的发生率显著更高、肌肉发育较差、肌张力较低且在贝利婴儿发育量表的心理运动指数上表现较差。这些儿童的母亲更常感觉他们主动不喜欢亲密的身体接触，母亲报告他们患感染、接受小手术和患慢性中耳炎的情况更多。综合来看，这些儿童体重增加不理想、粗大运动发育延迟以及母亲感觉他们“多病”和缺乏“可爱”，让人联想到非器质性发育不良。
