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冈比亚城市卫生中心围产儿死亡和低出生体重:一项前瞻性队列研究。

Perinatal deaths and low birthweight in an urban health centre in the Gambia: A prospective cohort study.

机构信息

Department of Global Heath and Infection, Brighton and Sussex Medical School, UK.

Brighton and Sussex Medical School, UK.

出版信息

Afr J Reprod Health. 2022 Mar;26(3):20-28. doi: 10.29063/ajrh2022/v26i3.3.

Abstract

Perinatal deaths (stillbirths after 28 weeks gestation and early neonatal deaths) are rarely reported separately but are the deaths most closely associated with complications during pregnancy, birth and the first days of life. We conducted a prospective cohort study to report perinatal deaths, late neonatal deaths and low birthweight babies as they occur. This cohort of birth outcomes from The Gambia was conducted between 2012 and 2016 and followed 1611 women attending a government-supported health center from the first antenatal visit to 28 days post-delivery. The outcome of the pregnancy was known for 1372 women (85.2%) and included 20 stillbirths and 12 early neonatal deaths. Of 1252 singleton babies with known birthweight 85 weighed less than 2500g (6.8%). Using multivariate analysis it was shown that women who attended the antenatal clinic four times or more were less likely to have a low birthweight baby than women who attended less than four times, OR 0.47 (95% CI:0.273-0.799). We conclude that frequent visits to the antenatal clinic are associated with better outcomes.

摘要

围产儿死亡(28 周后胎死和新生儿早期死亡)很少单独报告,但与妊娠、分娩和生命最初几天的并发症密切相关。我们进行了一项前瞻性队列研究,以报告围产儿死亡、晚期新生儿死亡和低出生体重儿的情况。该队列的出生结局来自冈比亚,于 2012 年至 2016 年进行,随访了 1611 名在政府支持的卫生中心接受产前检查的妇女,随访时间从第一次产前检查到分娩后 28 天。1372 名妇女(85.2%)的妊娠结局已知,包括 20 例死胎和 12 例新生儿早期死亡。在 1252 名已知出生体重的单胎婴儿中,85 名体重低于 2500 克(6.8%)。多变量分析显示,与少于 4 次就诊的妇女相比,产前检查就诊 4 次或以上的妇女发生低出生体重儿的可能性较小,比值比(OR)为 0.47(95%可信区间:0.273-0.799)。我们得出结论,频繁就诊于产前检查与更好的结局相关。

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