Department of Thoracic Surgery, Trakya University Faculty of Medicine, Edirne, Turkey.
Surg Laparosc Endosc Percutan Tech. 2023 Oct 1;33(5):487-492. doi: 10.1097/SLE.0000000000001213.
This study aimed to compare the outcomes of non-intubated video-assisted thoracic surgery (N-VATS) and intubated video-assisted thoracic surgery (I-VATS) for primary spontaneous pneumothorax (PSP).
We retrospectively analyzed 120 consecutive patients who underwent VATS for PSP. The patients were divided into N-VATS and I-VATS groups. Demographics, clinical characteristics, postoperative results, pain scores, follow-up results, and management were evaluated and compared between the groups. Local anesthesia and deep sedation (ketamine 2 mg/kg IV and propofol 2 mg/kg IV slow infusion) were administered under spontaneous ventilation in the N-VATS group.
The groups did not differ significantly in terms of age, sex, American Society of Anesthesiology score, pneumothorax side, or smoking history ( P >0.05). The mean operation time, anesthesia time, oral intake opening time, and mobilization time were significantly shorter in the N-VATS group (26.04±4.61 vs. 48.26±7.82 min, 42.14±6.40 vs. 98.16±12.4 min, 2.1±0.4 vs. 8.4±1.2 h, and 4.2±0.9 vs. 2.6±1.4 between N-VATS and I-VATS, respectively; P <0.05). The surgical outcomes did not differ in terms of minor complications (12%-13%) and recurrence rates (5.1%-6.4%) during a mean follow-up period of 88.4±10.2 mo. No cases of conversion to open surgery or mortality were observed. General anesthesia and intubation were not required for any patient in the N-VATS group.
Our results revealed no differences in minor complications or recurrence rates between groups. However, the N-VATS group had significantly shorter operation, anesthesia, oral intake opening, and mobilization times. The most important advantage of N-VATS for PSP is its fast recovery while avoiding the risks of general anesthesia and intubation. Further prospective studies with larger sample sizes are warranted.
本研究旨在比较非插管视频辅助胸腔手术(N-VATS)和插管视频辅助胸腔手术(I-VATS)治疗原发性自发性气胸(PSP)的结果。
我们回顾性分析了 120 例接受 VATS 治疗 PSP 的连续患者。患者分为 N-VATS 和 I-VATS 组。评估并比较了两组患者的人口统计学、临床特征、术后结果、疼痛评分、随访结果和处理。N-VATS 组在自主通气下给予局部麻醉和深度镇静(静脉注射氯胺酮 2mg/kg 和异丙酚 2mg/kg 缓慢输注)。
两组患者在年龄、性别、美国麻醉医师协会评分、气胸侧和吸烟史方面无显著差异(P>0.05)。N-VATS 组的手术时间、麻醉时间、口服摄入开放时间和活动时间明显短于 I-VATS 组(26.04±4.61 比 48.26±7.82min,42.14±6.40 比 98.16±12.4min,2.1±0.4 比 8.4±1.2h,4.2±0.9 比 2.6±1.4min;P<0.05)。在平均 88.4±10.2 个月的随访期间,两组的轻微并发症(12%-13%)和复发率(5.1%-6.4%)差异无统计学意义。两组均未发生中转开胸手术或死亡。N-VATS 组无患者需要全身麻醉和插管。
我们的结果显示两组在轻微并发症或复发率方面无差异。然而,N-VATS 组的手术、麻醉、口服摄入开放和活动时间明显缩短。N-VATS 治疗 PSP 的最重要优势是快速恢复,同时避免全身麻醉和插管的风险。需要进一步进行前瞻性研究,以获得更大的样本量。