Bursa City Hospital, Department of Cardiovasculary Surgery - Bursa, Turkey.
Bursa City Hospital, Department of Thoracic Surgery - Bursa, Turkey.
Rev Assoc Med Bras (1992). 2023 Aug 14;69(8):e20230226. doi: 10.1590/1806-9282.20230226. eCollection 2023.
This study aimed to analyze its predictive role in incipient postoperative atrial fibrillation by constructing an inflammatory prognostic index based on hematological and biochemical parameters in patients undergoing elective isolated coronary artery surgery accompanied by cardiopulmonary bypass.
The data of 343 patients who underwent coronary bypass surgery between May 2021 and July 2022 were evaluated. Multivariate logistic regression and recipient study characteristic curve analyses were studied by comparing the patients' hematological indices and basic clinical features between the two groups.
Logistic regression analysis showed that age (p<0.001), hypertension (p=0.01), and inflammatory prognostic index (p<0.001) were independent predictors of new-onset postoperative atrial fibrillation. To predict the development of postoperative atrial fibrillation, a cutoff value of 0.25 (77.8% sensitivity and 69.3% specificity) was determined for inflammatory prognostic index in the receiver-operating characteristic curve analysis (area under curve=0.798, 95% confidence interval 0.752-0.840).
Inflammatory prognostic index can be a noninvasive, easily available marker for predicting new-onset atrial fibrillation after coronary artery bypass surgery.
本研究旨在通过构建基于血液学和生化参数的炎症预后指数，分析其对体外循环下择期单纯冠状动脉旁路移植术患者术后早期心房颤动的预测作用。
评估了 2021 年 5 月至 2022 年 7 月期间接受冠状动脉旁路移植术的 343 例患者的数据。通过比较两组患者的血液学指标和基本临床特征，进行多变量逻辑回归和受试者工作特征曲线分析。
logistic 回归分析显示，年龄（p<0.001）、高血压（p=0.01）和炎症预后指数（p<0.001）是新发术后心房颤动的独立预测因素。为预测术后心房颤动的发生，在受试者工作特征曲线分析中确定炎症预后指数的截断值为 0.25（敏感性为 77.8%，特异性为 69.3%）（曲线下面积=0.798，95%置信区间 0.752-0.840）。
炎症预后指数可以作为预测冠状动脉旁路移植术后新发心房颤动的一种非侵入性、易于获得的标志物。
