针对 NY-ESO-1 的新型 TCR 推动肉瘤研究进展。
Pushing forward in sarcoma with a new TCR targeting NY-ESO-1.
机构信息
Northwestern University, Feinberg School of Medicine, Department of Medicine, Division of Oncology, Chicago, IL, USA.
Northwestern University, Feinberg School of Medicine, Department of Medicine, Division of Oncology, Chicago, IL, USA.
出版信息
Cell Rep Med. 2023 Aug 15;4(8):101159. doi: 10.1016/j.xcrm.2023.101159.
Abstract
A phase 1 trial demonstrating the safety and efficacy of a novel NY-ESO-1-specific TCR-T cells by Pan et al. is a major step forward for adoptive T cell therapy in the clinical practice of advanced soft tissue sarcomas.
摘要
潘等人开展的一项 I 期临床试验证明了新型 NY-ESO-1 特异性 TCR-T 细胞的安全性和有效性，这是过继性 T 细胞疗法在晚期软组织肉瘤临床实践中的重大进展。
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