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以颈淋巴结炎为表现的原发性耐异烟肼肺外结核:世界首例此类病例。

Primary Isoniazid Mono-Resistant Extrapulmonary Tuberculosis Presenting as Cervical Lymphadenitis: The World's First Case of Its Type.

作者信息

Yadav Sankalp

机构信息

Medicine, Shri Madan Lal Khurana Chest Clinic, New Delhi, IND.

出版信息

Cureus. 2023 Jul 15;15(7):e41937. doi: 10.7759/cureus.41937. eCollection 2023 Jul.

DOI:10.7759/cureus.41937
PMID:37588320
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10425288/
Abstract

Tuberculosis is commonly seen in endemic countries. Cases of primary drug resistance are rare. There is a paucity of data related to primary drug resistance at extrapulmonary sites. Herein, a case of primary isoniazid mono-resistant extrapulmonary tuberculosis of the multiple right cervical lymph nodes is presented. This patient reported multiple swellings and discharging sinuses. A battery of investigations with an eye for finding drug resistance led to a definite diagnosis. He was initiated on an anti-tubercular regimen per the national guidelines. A detailed literature search revealed that no such case of primary isoniazid mono-resistant extrapulmonary tuberculosis presenting as cervical lymphadenitis has ever been reported.

摘要

结核病在流行国家较为常见。原发性耐药病例很少见。关于肺外部位原发性耐药的数据很少。在此,报告一例右颈部多个淋巴结原发性异烟肼单耐药性肺外结核病例。该患者报告有多处肿胀和排脓窦道。一系列旨在发现耐药性的检查得出了明确诊断。根据国家指南,开始对他进行抗结核治疗。详细的文献检索显示,从未有过以颈淋巴结炎形式出现的原发性异烟肼单耐药性肺外结核病例的报道。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7696/10425288/f795ddc6bdb1/cureus-0015-00000041937-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7696/10425288/c6953745d559/cureus-0015-00000041937-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7696/10425288/f795ddc6bdb1/cureus-0015-00000041937-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7696/10425288/c6953745d559/cureus-0015-00000041937-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7696/10425288/f795ddc6bdb1/cureus-0015-00000041937-i02.jpg

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Primary Isoniazid Mono-Resistant Pulmonary Tuberculosis in a COVID-19-Positive Male: World's First Case of Its Kind in the Present Pandemic.
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Cureus. 2024 Jan 7;16(1):e51804. doi: 10.7759/cureus.51804. eCollection 2024 Jan.
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Primary Rifampicin Mono-Resistant Extrapulmonary Tuberculosis of the Knee Without Pulmonary Involvement: One of the First Cases of Its Type in an Immunocompetent Male.无肺部受累的原发性耐利福平膝关节肺外结核:免疫功能正常男性中首例此类病例之一。
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