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中国肥胖及其相关并发症的流行情况:一项涉及 1580 万成年人的横断面、真实世界研究。

Prevalence of obesity and associated complications in China: A cross-sectional, real-world study in 15.8 million adults.

机构信息

Department of Endocrinology, First Medical Center of Chinese PLA General Hospital, Beijing, China.

Biostatistics and Data Science, Novo Nordisk (China) Pharmaceuticals Co., Ltd, Beijing, China.

出版信息

Diabetes Obes Metab. 2023 Nov;25(11):3390-3399. doi: 10.1111/dom.15238. Epub 2023 Aug 17.

Abstract

AIM

To evaluate the prevalence of overweight/obesity and associated complications from a large, cross-sectional, nationwide database in China.

MATERIALS AND METHODS

Data were obtained from 519 Meinian health check-up centres across 243 cities. Eligible participants were aged ≥18 years, with a routine check-up in 2019 (N = 21 771 683) and complete height, weight, sex and region data. The unadjusted prevalence rates of overweight/obesity were calculated by age, sex and region. In addition, the nationwide prevalence rates of overweight and obesity were standardized according to the 2010 China census by age group and sex. The prevalence of obesity-related complications by body mass index (BMI) groups was calculated using logistic regression.

RESULTS

There were 15 770 094 eligible participants (median age 40 years; mean BMI 24.1 kg/m ; 52.8% male). By Chinese BMI classification, 34.8% were overweight and 14.1% were obese. Overweight and obesity were more prevalent in male than female participants (standardized: overweight 40.2% vs. 27.4%; obesity 17.6% vs. 9.6%, respectively). The prevalence of assessed complications was higher in participants with overweight/obesity versus those with normal BMI (P < 0.001 for trends). The most prevalent complications in participants with overweight/obesity were fatty liver disease, prediabetes, dyslipidaemia and hypertension. The number of complications increased with higher BMI.

CONCLUSIONS

Overweight/obesity and related complications are highly prevalent in this population. These data may better inform management and prevention public health strategies in China.

摘要

目的

从中国一个大型、跨地区、全国性的数据库中评估超重/肥胖的流行率及其相关并发症。

材料与方法

数据来自全国 243 个城市的 519 个美年健康检查中心。符合条件的参与者年龄≥18 岁,于 2019 年进行常规检查(N=21771683),并完整记录了身高、体重、性别和地区数据。按年龄、性别和地区计算了未经调整的超重/肥胖流行率。此外,根据 2010 年中国人口普查,按年龄组和性别对全国超重和肥胖的流行率进行了标准化。使用逻辑回归计算了各 BMI 组肥胖相关并发症的流行率。

结果

共有 15770094 名合格参与者(中位数年龄 40 岁;平均 BMI 24.1kg/m²;52.8%为男性)。按照中国 BMI 分类,34.8%为超重,14.1%为肥胖。与女性参与者相比,男性超重和肥胖更为常见(标准化:超重 40.2%比 27.4%;肥胖 17.6%比 9.6%)。与 BMI 正常的参与者相比,超重/肥胖的参与者发生各种评估并发症的概率更高(趋势 P<0.001)。超重/肥胖参与者中最常见的并发症是脂肪肝、糖尿病前期、血脂异常和高血压。随着 BMI 的升高,并发症的数量也随之增加。

结论

该人群中超重/肥胖及其相关并发症的发生率很高。这些数据可能会更好地为中国的管理和预防公共卫生策略提供信息。

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