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Genetically determined polymorphisms in drug oxidation.

作者信息

Jacqz E, Hall S D, Branch R A

出版信息

Hepatology. 1986 Sep-Oct;6(5):1020-32. doi: 10.1002/hep.1840060534.

DOI:10.1002/hep.1840060534
PMID:3758933
Abstract
摘要

相似文献

1
Genetically determined polymorphisms in drug oxidation.
Hepatology. 1986 Sep-Oct;6(5):1020-32. doi: 10.1002/hep.1840060534.
2
[Genetic polymorphism of oxidative drug metabolism. Therapeutic and toxicologic implications].[氧化药物代谢的基因多态性。治疗和毒理学意义]
Internist (Berl). 1983 Mar;24(3):117-27.
3
Polymorphic drug oxidation in humans.人类的多态性药物氧化
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4
Genetic polymorphisms of drug metabolism.药物代谢的基因多态性
Prog Liver Dis. 1990;9:307-23.
5
The molecular mechanisms of two common polymorphisms of drug oxidation--evidence for functional changes in cytochrome P-450 isozymes catalysing bufuralol and mephenytoin oxidation.药物氧化两种常见多态性的分子机制——催化布呋洛尔和美芬妥因氧化的细胞色素P-450同工酶功能改变的证据
Xenobiotica. 1986 May;16(5):449-64. doi: 10.3109/00498258609050251.
6
Genetic polymorphism of drug metabolism in humans.人类药物代谢的基因多态性
Adv Exp Med Biol. 1991;283:627-40. doi: 10.1007/978-1-4684-5877-0_79.
7
Pharmacogenetic polymorphism of drug metabolism.
N Z Med J. 1984 Aug 22;97(762):567-9.
8
Molecular mechanisms of genetic polymorphisms of drug metabolism.药物代谢遗传多态性的分子机制
Annu Rev Pharmacol Toxicol. 1997;37:269-96. doi: 10.1146/annurev.pharmtox.37.1.269.
9
Stereo- and regioselectivity of hepatic oxidation in man--effect of the debrisoquine/sparteine phenotype on bufuralol hydroxylation.人体肝脏氧化的立体选择性和区域选择性——去甲异喹胍/鹰爪豆碱表型对丁呋洛尔羟基化作用的影响
Eur J Clin Pharmacol. 1986;31(3):313-8. doi: 10.1007/BF00981130.
10
Enzymatic basis of the debrisoquine/sparteine-type genetic polymorphism of drug oxidation. Characterization of bufuralol 1'-hydroxylation in liver microsomes of in vivo phenotyped carriers of the genetic deficiency.药物氧化的去甲丙咪嗪/鹰爪豆碱型遗传多态性的酶学基础。对遗传缺陷的体内表型携带者肝脏微粒体中布呋洛尔1'-羟化作用的表征。
Biochem Pharmacol. 1987 Dec 1;36(23):4145-52. doi: 10.1016/0006-2952(87)90573-9.

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Clinical significance of genetic influences on cardiovascular drug metabolism.基因对心血管药物代谢影响的临床意义。
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Thiopurine methyltransferase activity in a French population: h.p.l.c. assay conditions and effects of drugs and inhibitors.法国人群中的硫嘌呤甲基转移酶活性:高效液相色谱法检测条件及药物和抑制剂的影响
Br J Clin Pharmacol. 1994 Jul;38(1):1-8. doi: 10.1111/j.1365-2125.1994.tb04314.x.
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Clinical trials and transethnic pharmacology.临床试验与跨种族药理学。
Drug Saf. 1994 Nov;11(5):378-91. doi: 10.2165/00002018-199411050-00005.
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Debrisoquine hydroxylase gene polymorphism in Parkinson's disease and amyotrophic lateral sclerosis.帕金森病和肌萎缩侧索硬化症中的异喹胍羟化酶基因多态性
J Neurol Neurosurg Psychiatry. 1995 Jan;58(1):109. doi: 10.1136/jnnp.58.1.109.
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Antipyrine disposition in obesity: evidence for negligible effect of obesity on hepatic oxidative metabolism.肥胖患者中安替比林的处置:肥胖对肝脏氧化代谢影响可忽略不计的证据。
Eur J Clin Pharmacol. 1995;47(6):525-30. doi: 10.1007/BF00193706.
6
Cytochrome P-450IID6 phenotyping in cancer patients: debrisoquin and dextromethorphan as probes.癌症患者细胞色素P-450IID6表型分析:以异喹胍和右美沙芬作为探针
Cancer Chemother Pharmacol. 1995;36(2):125-8. doi: 10.1007/BF00689196.
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Clinical significance of the trimethadione tolerance test in chronic hepatitis: a useful indicator of hepatic drug metabolizing capacity.三甲双酮耐受试验在慢性肝炎中的临床意义:肝脏药物代谢能力的一项有用指标。
J Gastroenterol. 1995 Aug;30(4):478-84. doi: 10.1007/BF02347564.
8
Prevalence of drug hydroxylator phenotypes in Belgium.比利时药物羟化酶表型的流行情况。
Eur J Clin Pharmacol. 1987;33(4):439-40. doi: 10.1007/BF00637647.
9
[The development of pharmacogenetics--a retrospective on the 75th birthday of Hans Herken].
Klin Wochenschr. 1988 Mar 15;66(6):229-35. doi: 10.1007/BF01748161.
10
Debrisoquine oxidation in a Finnish population: the effect of oral contraceptives on the metabolic ratio.芬兰人群中的异喹胍氧化:口服避孕药对代谢率的影响。
Br J Clin Pharmacol. 1988 Dec;26(6):791-5. doi: 10.1111/j.1365-2125.1988.tb05321.x.