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Prevalence of drug hydroxylator phenotypes in Belgium.

作者信息

Leclercq V, Desager J P, van Nieuwenhuyze Y, Harvengt C

机构信息

Laboratoire de Pharmacothérapie, Université Catholique de Louvain, Bruxelles, Belgium.

出版信息

Eur J Clin Pharmacol. 1987;33(4):439-40. doi: 10.1007/BF00637647.

DOI:10.1007/BF00637647
PMID:3443153
Abstract
摘要

相似文献

1
Prevalence of drug hydroxylator phenotypes in Belgium.比利时药物羟化酶表型的流行情况。
Eur J Clin Pharmacol. 1987;33(4):439-40. doi: 10.1007/BF00637647.
2
Drug hydroxylator phenotype in Hungary.
Eur J Clin Pharmacol. 1987;32(3):325. doi: 10.1007/BF00607584.
3
The debrisoquin hydroxylation phenotype does not predict the metabolism of phenytoin.异喹胍羟基化表型不能预测苯妥英的代谢。
Clin Pharmacol Ther. 1987 Sep;42(3):326-33. doi: 10.1038/clpt.1987.156.
4
Hydroxylation of desmethylimipramine: dependence on the debrisoquin hydroxylation phenotype.
Clin Pharmacol Ther. 1987 Mar;41(3):314-9. doi: 10.1038/clpt.1987.33.
5
A family study of genetic and environmental factors determining polymorphic hydroxylation of debrisoquin.一项关于决定异喹胍多态性羟化的遗传和环境因素的家族研究。
Clin Pharmacol Ther. 1985 Oct;38(4):394-401. doi: 10.1038/clpt.1985.193.
6
Debrisoquine hydroxylation phenotypes in healthy volunteers.健康志愿者中的异喹胍羟化表型
Lancet. 1989 Jun 17;1(8651):1398. doi: 10.1016/s0140-6736(89)92854-7.
7
Rapid conjugation in an extremely rapid hydroxylator of debrisoquine: a case report supporting a coregulation of certain phase I and II metabolic reactions.异喹胍超快羟化者中的快速结合:支持某些I相和II相代谢反应共同调节的病例报告
Ther Drug Monit. 1988;10(2):242-4. doi: 10.1097/00007691-198802000-00023.
8
[A survey of debrisoquin hydroxylation polymorphism].[异喹胍羟基化多态性的调查]
Orv Hetil. 1986 Sep 21;127(38):2299-301.
9
Polymorphic debrisoquin hydroxylation in 757 Swedish subjects.
Clin Pharmacol Ther. 1988 Oct;44(4):431-5. doi: 10.1038/clpt.1988.176.
10
Slow hydroxylation of nortriptyline and concomitant poor debrisoquine hydroxylation: clinical implications.去甲替林的缓慢羟化作用及同时存在的异喹胍羟化不良:临床意义。
Lancet. 1981 Mar 7;1(8219):560-1. doi: 10.1016/s0140-6736(81)92894-4.

引用本文的文献

1
Dextromethorphan O-demethylation polymorphism in Jordanians.
Eur J Clin Pharmacol. 1993;45(3):271-3. doi: 10.1007/BF00315395.
2
Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations.欧洲人群中异喹胍和甲妥英的羟化多态性
Eur J Clin Pharmacol. 1990;39(6):533-7. doi: 10.1007/BF00316090.

本文引用的文献

1
A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.对英国白人人群中异喹胍氧化遗传多态性的家系及群体研究。
J Med Genet. 1980 Apr;17(2):102-5. doi: 10.1136/jmg.17.2.102.
2
The genetic control of bufuralol metabolism in man.
Eur J Drug Metab Pharmacokinet. 1982 Jan-Mar;7(1):73-7. doi: 10.1007/BF03189547.
3
High plasma concentrations of beta-receptor blocking drugs and deficient debrisoquine hydroxylation.β受体阻断药物的高血浆浓度与异喹胍羟化不足。
Lancet. 1982 Feb 6;1(8267):333. doi: 10.1016/s0140-6736(82)91583-5.
4
Genetically determined polymorphisms in drug oxidation.
Hepatology. 1986 Sep-Oct;6(5):1020-32. doi: 10.1002/hep.1840060534.
5
Determination of debrisoquine and its 4-hydroxy metabolite in biological fluids by gas chromatography with flame-ionization and nitrogen-selective detection.采用气相色谱-火焰离子化和氮选择性检测法测定生物流体中的异喹胍及其4-羟基代谢物。
J Chromatogr. 1977 Mar 11;133(1):161-6. doi: 10.1016/s0021-9673(00)89216-x.
6
Defective N-oxidation of sparteine in man: a new pharmacogenetic defect.人司巴丁N-氧化缺陷:一种新的药物遗传学缺陷。
Eur J Clin Pharmacol. 1979 Sep;16(3):183-7. doi: 10.1007/BF00562059.