丹麦在 COVID-19 大流行期间全国范围内的乳房 X 光筛检参与情况：一项观察性研究。

Nationwide mammography screening participation in Denmark during the COVID-19 pandemic: An observational study.

机构信息

The Danish Clinical Quality Program - National Clinical Registries (RKKP), Aarhus N, Denmark.

University Research Clinic for Cancer Screening, Department of Public Health Programmes, Randers Regional Hospital, Randers, Denmark.

出版信息

Elife. 2023 Aug 17;12:e83541. doi: 10.7554/eLife.83541.

DOI:10.7554/eLife.83541

PMID:37589381

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10513477/

Abstract

BACKGROUND

In most of the world, the mammography screening programmes were paused at the start of the pandemic, whilst mammography screening continued in Denmark. We examined the mammography screening participation during the COVID-19 pandemic in Denmark.

METHODS

The study population comprised all women aged 50-69 years old invited to participate in mammography screening from 2016 to 2021 in Denmark based on data from the Danish Quality Database for Mammography Screening in combination with population-based registries. Using a generalised linear model, we estimated prevalence ratios (PRs) and 95% confidence intervals (CIs) of mammography screening participation within 90, 180, and 365 d since invitation during the pandemic in comparison with the previous years adjusting for age, year and month of invitation.

RESULTS

The study comprised 1,828,791 invitations among 847,766 women. Before the pandemic, 80.2% of invitations resulted in participation in mammography screening within 90 d, 82.7% within 180 d, and 83.1% within 365 d. At the start of the pandemic, the participation in screening within 90 d was reduced to 69.9% for those invited in pre-lockdown and to 76.5% for those invited in first lockdown. Extending the length of follow-up time to 365 d only a minor overall reduction was observed (PR = 0.94; 95% CI: 0.93-0.95 in pre-lockdown and PR = 0.97; 95% CI: 0.96-0.97 in first lockdown). A lower participation was, however, seen among immigrants and among women with a low income.

CONCLUSIONS

The short-term participation in mammography screening was reduced at the start of the pandemic, whilst only a minor reduction in the overall participation was observed with longer follow-up time, indicating that women postponed screening. Some groups of women, nonetheless, had a lower participation, indicating that the social inequity in screening participation was exacerbated during the pandemic.

FUNDING

The study was funded by the Danish Cancer Society Scientific Committee (grant number R321-A17417) and the Danish regions.

摘要

背景

在世界大部分地区，疫情开始时，乳腺 X 线筛查项目暂停，而丹麦仍继续进行乳腺 X 线筛查。我们研究了丹麦在 COVID-19 大流行期间的乳腺 X 线筛查参与情况。

方法

研究人群包括根据丹麦乳腺 X 线筛查质量数据库的数据，结合基于人群的登记册，邀请参加 2016 年至 2021 年乳腺 X 线筛查的所有 50-69 岁女性。使用广义线性模型，我们估计了在疫情期间与前几年相比，自邀请后 90、180 和 365 天内乳腺 X 线筛查参与的患病率比（PR）和 95%置信区间（CI），并根据年龄、邀请的年份和月份进行了调整。

结果

该研究共包括 847766 名女性中的 1828791 次邀请。在疫情之前，80.2%的邀请在 90 天内导致了乳腺 X 线筛查的参与，82.7%在 180 天内，83.1%在 365 天内。在疫情开始时，邀请在封锁前的人在 90 天内的筛查参与率下降到 69.9%，邀请在首次封锁期间的人下降到 76.5%。将随访时间延长至 365 天，仅观察到总体参与率略有下降（封锁前的 PR = 0.94；95%CI：0.93-0.95，首次封锁的 PR = 0.97；95%CI：0.96-0.97）。然而，移民和低收入女性的参与率较低。