Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, WC1N 3JH, UK.
Paediatric Infectious Diseases, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Pediatr Radiol. 2024 Apr;54(4):530-547. doi: 10.1007/s00247-023-05735-1. Epub 2023 Aug 17.
Pulmonary infection is the leading cause of infectious morbidity and mortality in children with immune defects. We provide a comprehensive review of lung infections in immunocompromised children, with a focus on imaging findings and imaging-based management. We include an overview of the immune defences of the respiratory tract, the aetiologies of immune defects in children, the features of specific infections and important differential diagnoses and describe diagnostic strategies using imaging and non-imaging-based techniques.
肺部感染是导致免疫缺陷儿童发生感染性发病率和死亡率的主要原因。我们全面综述了免疫功能低下儿童肺部感染的影像学表现和基于影像学的管理方法，包括呼吸道的免疫防御机制、儿童免疫缺陷的病因、特定感染的特征以及重要的鉴别诊断，并描述了使用影像学和非影像学技术的诊断策略。
