Department of Psychiatry, Helsinki University Hospital, Helsinki, Finland.
Finnish Psychological Association, Helsinki, Finland.
J Med Internet Res. 2023 Aug 17;25:e45362. doi: 10.2196/45362.
Internet-delivered cognitive behavioral therapy (iCBT) is effective in the treatment of anxiety disorders. iCBT clinical trials use relatively long and time-consuming disorder-specific rather than transdiagnostic anxiety measurements. Overall Anxiety Severity and Impairment Scale (OASIS) is a brief self-report scale that could offer a universal, easy-to-use anxiety measurement option in disorder-specific and transdiagnostic iCBT programs.
We aimed to investigate relationships between OASIS and disorder-specific instruments in iCBT. We expected these relationships to be positive.
We investigated patients in original nationwide iCBT programs for generalized anxiety disorder (GAD), obsessive-compulsive disorder, panic disorder, and social anxiety disorder, which were administered by Helsinki University Hospital, Finland. In each program, anxiety symptoms were measured using both disorder-specific scales (the 7-item Generalized Anxiety Disorder scale, Penn State Worry Questionnaire, revised Obsessive-Compulsive Inventory, Panic Disorder Severity Scale, and Social Phobia Inventory) and by OASIS. A general linear model for repeated measures (mixed models) and interaction analysis were used for investigating the changes and relationships in the mean scores of OASIS and disorder-specific scales from the first session to the last one.
The main effect of linear mixed models indicated a distinct positive association between OASIS and disorder-specific scale scores. Interaction analysis demonstrated relatively stable associations between OASIS and the revised Obsessive-Compulsive Inventory (F=0.09; 95% CI 0.090-0.277; P=.32), and OASIS and the Panic Disorder Severity Scale (F=-0.02; 95% CI -0.108 to -0.065; P=.63) from first the session to the last one, while the 7-item Generalized Anxiety Disorder scale (F=-0.06; 95% CI -0.109 to -0.017; P=.007), Penn State Worry Questionnaire (F=-0.52; 95% CI -0.620 to -0.437; P<.001), and Social Phobia Inventory (F=-0.39; 95% CI -0.596 to -0.187; P<.001) interrelated with OASIS more strongly at the last session than at the first one.
OASIS demonstrates clear and relatively stable associations with disorder-specific symptom measures. Thus, OASIS might serve as an outcome measurement instrument for disorder-specific and plausibly transdiagnostic iCBT programs for anxiety disorders in regular clinical practice.
互联网认知行为疗法（iCBT）在治疗焦虑症方面是有效的。iCBT 临床试验使用相对较长且耗时的特定疾病而非跨诊断焦虑测量方法。总体焦虑严重程度和障碍损害量表（OASIS）是一种简短的自我报告量表，可为特定疾病和跨诊断 iCBT 计划中的通用、易于使用的焦虑测量选项提供支持。
我们旨在研究 OASIS 与 iCBT 中的特定疾病量表之间的关系。我们预计这些关系是积极的。
我们调查了芬兰赫尔辛基大学医院管理的针对广泛性焦虑症（GAD）、强迫症、惊恐障碍和社交焦虑症的全国性 iCBT 原始计划中的患者。在每个计划中，使用特定疾病量表（7 项广泛性焦虑症量表、宾夕法尼亚州担忧问卷、修订后的强迫症量表、惊恐障碍严重程度量表和社交恐惧症量表）和 OASIS 来测量焦虑症状。使用重复测量的一般线性模型（混合模型）和交互分析来研究从第一次会议到最后一次会议 OASIS 和特定疾病量表的平均分数的变化和关系。
线性混合模型的主要效应表明，OASIS 与特定疾病量表的分数之间存在明显的正相关。交互分析表明，OASIS 与修订后的强迫症量表（F=0.09；95%CI 0.090-0.277；P=.32）和 OASIS 与惊恐障碍严重程度量表（F=-0.02；95%CI -0.108 至 -0.065；P=.63）之间的关联相对稳定，而 7 项广泛性焦虑症量表（F=-0.06；95%CI -0.109 至 -0.017；P=.007）、宾夕法尼亚州担忧问卷（F=-0.52；95%CI -0.620 至 -0.437；P<.001）和社交恐惧症量表（F=-0.39；95%CI -0.596 至 -0.187；P<.001）在最后一次会议上与 OASIS 的关联比第一次会议更紧密。
OASIS 与特定疾病症状测量方法之间存在明确且相对稳定的关联。因此，OASIS 可能成为特定疾病和合理跨诊断 iCBT 计划中焦虑症的常规临床实践中的结果测量工具。
