Atrium Health Carolinas Medical Center Family Medicine and Wake Forest School of Medicine, Charlotte, North Carolina.
Am Fam Physician. 2023 Aug;108(2):159-165.
In the United States, approximately 2% to 3% of adults and 8% of children have a food allergy. Allergic reactions range from minor pruritus to life-threatening anaphylaxis. These allergies often lead to significant anxiety and costs for patients and caregivers. Common food allergies include peanuts, cow's milk, shellfish, tree nuts, egg, fish, soy, and wheat. Peanut allergy, the most common, is the leading cause of life-threatening anaphylaxis. Children with asthma, allergic rhinitis, atopic dermatitis, or an allergy to insect venom, medications, or latex are at an increased risk of developing food allergies. Diagnosis of food allergy starts with a detailed, allergy-focused history. Serum immunoglobulin E and skin prick testing provide reliable information regarding food allergy diagnoses. Primary treatment involves elimination of the offending food from the diet. Prevention strategies proven to decrease the risk of developing a food allergy include restricting exposure to cow's milk in the first three days of life and early sequential exposure to allergenic foods starting between four and six months of age. Exclusive breastfeeding for three to four months reduces the likelihood of developing eczema and asthma but does not reduce development of food allergies. Most children eventually outgrow allergies to cow's milk, egg, soy, and wheat. However, allergies to tree nuts, peanuts, and shellfish are more likely to be lifelong.
在美国,约有 2%至 3%的成年人和 8%的儿童患有食物过敏症。过敏反应的范围从轻微瘙痒到危及生命的过敏反应。这些过敏症经常给患者和护理人员带来严重的焦虑和费用。常见的食物过敏包括花生、牛奶、贝类、坚果、鸡蛋、鱼类、大豆和小麦。花生过敏是最常见的过敏症,也是导致危及生命的过敏反应的主要原因。患有哮喘、过敏性鼻炎、特应性皮炎或对昆虫毒液、药物或乳胶过敏的儿童患食物过敏的风险增加。食物过敏的诊断始于详细的、以过敏为重点的病史。血清免疫球蛋白 E 和皮肤点刺试验为食物过敏的诊断提供了可靠的信息。主要治疗方法是从饮食中消除引起过敏的食物。已证明可降低食物过敏风险的预防策略包括限制生命最初三天接触牛奶,以及在四至六个月龄时开始逐步接触致敏食物。母乳喂养三到四个月可降低湿疹和哮喘的发病几率,但并不能降低食物过敏的发病几率。大多数儿童最终会对牛奶、鸡蛋、大豆和小麦过敏。然而,对坚果、花生和贝类过敏更可能是终身的。