Suppr超能文献

原发性胸骨骨髓炎:一例报告。

Primary sternal osteomyelitis: A case report.

作者信息

Al Ani Amer, Abdelmonem Khadiga, Forsat Kowthar, Alqaderi Nour, Teir Hajar

机构信息

College of Medicine, Ajman university, Ajman, United Arab Emirates.

College of Medicine, Ajman university, Ajman, United Arab Emirates.

出版信息

Int J Surg Case Rep. 2023 Sep;110:108654. doi: 10.1016/j.ijscr.2023.108654. Epub 2023 Aug 13.

Abstract

INTRODUCTION

Primary sternal osteomyelitis is a rare condition that is frequently caused by Staphylococcus aureus. It is often confused with other cardiac and pulmonary conditions. Early antimicrobial treatment and surgical debridement is the cornerstone of treatment.

CASE PRESENTATION

A 51-year-old male adult came to the emergency room (ER) with a 2-week history of chest pain, fever, and malaise. His past medical history was unremarkable. Examination revealed a tender anterior chest wall swelling. White Blood Cells (WBCs) (21.6 × 10)/mm) and C-reactive protein (CRP) (294.10 mg/L) were elevated. Pus from the swelling and blood samples were sent for culture and sensitivity. Electrocardiogram (ECG) was normal and a computed tomography (CT) scan of the chest showed a large dense anterior chest wall abscess extending deep in the chest and to both axillae which caused bony erosion of the sternum. Incision and drainage of the abscess were performed, followed by surgical debridement of the wound. Cultures along the course showed both Staphylococcus aureus and Enterococcus. The patient improved gradually and 2 months after his initial presentation, he became free of symptoms, and CT has shown complete resolution.

DISCUSSION

Osteomyelitis usually happens after an external bacterium seeds the bone where it begins to grow and thrive, leading to the destruction and pus accumulation under the periosteum. For the treatment, identifying the causative agent is critical in giving intravenous (IV) antibiotic. Thereafter, incision and drainage of an abscess can be performed, similar to what was done with the patient mentioned. Radiography, specifically a CT scan, is crucial as it clearly reveals bony margins and can differentiate between a sequestrum and an involucrum. It also identifies cortical erosion, intraosseous gases and periosteal reactions.

CONCLUSION

Sternal osteomyelitis can have a nonspecific clinical presentation. Laboratory investigations and radiological findings are crucial for a prompt diagnosis. To prevent the progression of the disease and complications, early intervention is vital to ensure a good prognosis.

摘要

引言

原发性胸骨骨髓炎是一种罕见疾病,常由金黄色葡萄球菌引起。它常与其他心脏和肺部疾病相混淆。早期抗菌治疗和手术清创是治疗的基石。

病例介绍

一名51岁成年男性因胸痛、发热和全身不适2周前来急诊室就诊。他既往病史无异常。检查发现前胸壁有压痛性肿胀。白细胞(WBCs)(21.6×10⁹/mm³)和C反应蛋白(CRP)(294.10mg/L)升高。从肿胀处抽取的脓液和血样送去做培养及药敏试验。心电图(ECG)正常,胸部计算机断层扫描(CT)显示前胸壁有一个大的致密脓肿,深入胸部并延伸至双侧腋窝,导致胸骨骨质侵蚀。对脓肿进行了切开引流,随后对伤口进行了手术清创。病程中的培养显示有金黄色葡萄球菌和肠球菌。患者逐渐好转,初次就诊2个月后,症状消失,CT显示完全消退。

讨论

骨髓炎通常在外源性细菌定植于骨骼并开始生长繁殖后发生,导致骨膜下破坏和脓液积聚。对于治疗而言,确定病原体对于给予静脉抗生素至关重要。此后,可以像对上述患者那样进行脓肿切开引流。影像学检查,特别是CT扫描,至关重要,因为它能清晰显示骨质边缘,可区分死骨和骨痂,还能识别皮质侵蚀、骨内气体和骨膜反应。

结论

胸骨骨髓炎可具有非特异性临床表现。实验室检查和影像学检查结果对于及时诊断至关重要。为防止疾病进展和并发症,早期干预对于确保良好预后至关重要。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验