Department of Cardiovascular Surgery, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami, Sagamihara, Kanagawa, 252-0374, Japan.
Gen Thorac Cardiovasc Surg. 2024 Apr;72(4):225-231. doi: 10.1007/s11748-023-01967-y. Epub 2023 Aug 17.
This single-center retrospective study evaluated early and midterm outcomes of 100 consecutive patients with type A intramural hematoma.
Initial watch-and-wait strategy was indicated if the maximum aortic diameter was < 50 mm, pain score was < 3/10 on the numerical rating scale, and no ulcer-like projection was observed in the ascending aorta. The primary endpoints of this study were all-cause and aorta-related deaths, and the secondary endpoint was aortic events.
Initial watch-and-wait strategy was indicated in 52 patients. Emergency aortic repair was indicated in the remaining 48 patients; 2, 31, and 15 patients died before surgery, underwent emergency surgery, and declined emergency surgery, respectively. Among the watch-and-wait group, 11 (21%) patients underwent aortic repair during hospitalization. In-hospital mortality rates, 5-year survival rates, and 5-year freedom from aorta-related death were not significantly different between the initial watch-and-wait strategy and emergency surgery (2% vs. 6%, 92% vs. 82%, and 100% vs. 94%, respectively). In the initial watch-and-wait strategy group, 5-year freedom from aortic events and freedom from aortic events involving the ascending aorta were 60% and 66%, respectively.
The early and midterm outcomes with the initial watch-and-wait strategy in patients with type A intramural hematoma with a maximum aortic diameter of ≤ 50 mm, pain score of ≤ 3/10, and no ulcer-like projection in the ascending aorta were favorable with no aorta-related death.
本单中心回顾性研究评估了 100 例连续型壁内血肿患者的早期和中期结果。
如果最大主动脉直径<50mm,疼痛评分<数字评分量表的 3/10,且升主动脉无溃疡样突起,则采用初始观察等待策略。本研究的主要终点是全因死亡率和主动脉相关死亡率,次要终点是主动脉事件。
52 例患者采用初始观察等待策略,其余 48 例患者需紧急主动脉修复;分别有 2 例、31 例和 15 例患者在术前死亡、接受紧急手术和拒绝紧急手术。在观察等待组中,11 例(21%)患者在住院期间接受了主动脉修复。观察等待组和紧急手术组的院内死亡率、5 年生存率和 5 年免于主动脉相关死亡率无显著差异(2% vs. 6%,92% vs. 82%,100% vs. 94%)。在初始观察等待策略组中,5 年免于主动脉事件和免于涉及升主动脉的主动脉事件的比例分别为 60%和 66%。
对于最大主动脉直径≤50mm、疼痛评分≤3/10、升主动脉无溃疡样突起的壁内血肿患者,采用初始观察等待策略的早期和中期结果良好,无主动脉相关死亡。