Linden-Castro Edgar, Pelayo-Nieto Marcela, Alias-Melgar Alejandro, Ramírez-Galindo Iván, Espinosa-Perez-Grovas Daniel, Ordaz-Macias Diego, Catalan-Quinto Gabriel
Urology Department, Centro Médico Nacional 20 de Noviembre, Mexico City, Mexico.
Urol Pract. 2016 Jan;3(1):32-35. doi: 10.1016/j.urpr.2015.04.003. Epub 2015 Oct 13.
We evaluated the psychological impact on patients caused by transrectal prostate biopsy and the emotional stress in those with a positive prostate cancer finding.
We performed a psychological evaluation of 328 men who underwent transrectal prostate biopsy using HADS (Hospital Anxiety and Depression Scale) at 3 time points. In addition we analyzed events related to the procedure, compared anxiety and depression levels in men with a negative result vs those diagnosed with prostate cancer, and evaluated anxiety and depression associated with events related to the procedure.
Of the 328 men 99.08% completed the evaluation, including 51.2% with a biopsy positive for prostate cancer and 48.8% with a negative prostate cancer result. The group with a positive biopsy scored an average of 6.85 in the anxiety category and 3.48 for depressive symptoms with a 2.02 point difference in respect to the original evaluation (p = 0.01). Prostate cancer with prostate specific antigen greater than 20 ng/ml was associated with significant anxiety (p = 0.03).
Biopsy positive for prostate cancer with prostate specific antigen greater than 20 ng/ml is associated with significant anxiety. However, events related to the procedure and marital status are not associated with significant anxiety.
我们评估了经直肠前列腺活检对患者造成的心理影响以及前列腺癌检查结果呈阳性患者的情绪压力。
我们对328名接受经直肠前列腺活检的男性进行了心理评估，在三个时间点使用医院焦虑抑郁量表（HADS）。此外，我们分析了与该检查相关的事件，比较了检查结果为阴性的男性与被诊断为前列腺癌的男性的焦虑和抑郁水平，并评估了与该检查相关事件所伴发的焦虑和抑郁。
328名男性中99.08%完成了评估，其中51.2%的前列腺活检结果为癌症阳性，48.8%的前列腺癌检查结果为阴性。活检结果为阳性的组在焦虑类别中的平均得分为6.85分，抑郁症状得分为3.48分，与最初评估相比有2.02分的差异（p = 0.01）。前列腺特异性抗原大于20 ng/ml的前列腺癌与显著焦虑相关（p = 0.03）。
前列腺特异性抗原大于20 ng/ml的前列腺癌活检阳性与显著焦虑相关。然而，与该检查相关的事件和婚姻状况与显著焦虑无关。
