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比较骨盆骨折尿道损伤管理策略成本的决策分析模型

Decision Analysis Model Comparing Cost of Management Strategies for Pelvic Fracture Urethral Injuries.

作者信息

Tausch Timothy J, Lotan Yair, Zhao Lee, Morey Allen F

机构信息

Department of Urology, UT Southwestern Medical Center, Dallas, Texas.

出版信息

Urol Pract. 2017 Jul;4(4):285-289. doi: 10.1016/j.urpr.2016.07.004. Epub 2016 Oct 15.

Abstract

INTRODUCTION

We compare the costs associated with primary endoscopic realignment vs delayed elective bulbomembranous anastomotic urethroplasty after initial management of pelvic fracture urethral injuries with suprapubic tubes.

METHODS

Decision analysis was performed comparing the costs associated with suprapubic tube placement with a definitive bulbomembranous urethroplasty performed 2 to 3 months after injury to those associated with primary endoscopic realignment. Model assumptions based on literature review included success rates of 30% for primary endoscopic realignment, 92% for bulbomembranous urethroplasty and 50% for direct vision internal urethrotomy. Using an institutional patient database of patients undergoing suprapubic tube placement, bulbomembranous urethroplasty and direct vision internal urethrotomy, costs were estimated based on hospital and operating room costs and Medicare reimbursement rates. Sensitivity analyses were performed by varying model assumptions. Using data from the Nationwide Inpatient Sample and the National Trauma Data Bank®, the annual incidence of pelvic fracture urethral injuries nationwide was estimated.

RESULTS

The total average cost of treating a pelvic fracture urethral injury with attempted primary endoscopic realignment is $11,043 vs $9,743 for suprapubic tube with elective bulbomembranous urethroplasty, for a savings of $1,300 (12%) per patient. For primary endoscopic realignment to be preferred, a success rate of 40% or better would be necessary. In addition, cost analysis calculation revealed that when bulbomembranous urethroplasty demonstrates an efficacy of 78% or greater, then suprapubic tube and elective bulbomembranous urethroplasty become more cost-effective than primary endoscopic realignment.

CONCLUSIONS

Given the added costs and variable outcomes of primary endoscopic realignment and subsequent endoscopic interventions, the durability of definitive urethroplasty appears to be cost-effective in treating men with pelvic fracture urethral injuries.

摘要

引言

我们比较了耻骨上造瘘管对骨盆骨折所致尿道损伤进行初始处理后,一期内镜下复位与延迟择期球膜部吻合尿道成形术的相关费用。

方法

进行决策分析,比较耻骨上造瘘管置入并在损伤后2至3个月进行确定性球膜部尿道成形术与一期内镜下复位的相关费用。基于文献综述的模型假设包括:一期内镜下复位成功率为30%,球膜部尿道成形术成功率为92%,直视下内尿道切开术成功率为50%。利用机构内接受耻骨上造瘘管置入、球膜部尿道成形术和直视下内尿道切开术患者的数据库,根据医院和手术室费用以及医疗保险报销率估算费用。通过改变模型假设进行敏感性分析。利用来自全国住院患者样本和国家创伤数据库®的数据,估算全国骨盆骨折所致尿道损伤的年发病率。

结果

尝试一期内镜下复位治疗骨盆骨折所致尿道损伤的总平均费用为11,043美元,而耻骨上造瘘管置入并择期行球膜部尿道成形术的费用为9,743美元,每位患者节省1,300美元(12%)。若要优先选择一期内镜下复位,则成功率需达到40%或更高。此外,成本分析计算表明,当球膜部尿道成形术的疗效达到78%或更高时,耻骨上造瘘管置入并择期行球膜部尿道成形术比一期内镜下复位更具成本效益。

结论

鉴于一期内镜下复位及后续内镜干预的额外费用和可变结果,确定性尿道成形术的持久性在治疗骨盆骨折所致尿道损伤的男性患者中似乎具有成本效益。

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