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水和乙二醇中钴铁氧体纳米颗粒通过纤毛环的电动渗透流:生物医学应用。

Electroosmotic flow of cobalt-ferrite nanoparticles in water and ethylene glycol through a ciliary annulus: A biomedical application.

机构信息

Department of Mathematics, Division of Science and Technology, University of Education, Lahore, Pakistan.

Department of Mathematics and Statistics, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Kingdom of Saudi Arabia.

出版信息

Electrophoresis. 2024 Jul;45(13-14):1198-1211. doi: 10.1002/elps.202300137. Epub 2023 Aug 17.

Abstract

Unique magnetic characteristics of cobalt-ferrite nanoparticles make them suitable for biological imaging and therapeutic applications. Understanding their activity in nanofluids via the ciliary annulus could lead to better contrast agents for magnetic resonance imaging and improved cancer therapy and other medical therapies. This article provides a comprehensive analysis of the theoretical conclusions regarding the transport of a nanofluid by electroosmosis across a ciliary annulus. The nanofluid consists of cobalt-ferrite nanoparticles (CoFeO), water (HO), and ethylene glycol (CHO). As part of the investigation into constructing a physical model, mathematical analysis is performed based on the conservation of mass, momentum, and energy. Dimension-free analysis and mathematical constraints are utilized to learn more about the system. By generating differential equations and including suitable boundary conditions, one can obtain exact solutions, which can then be visually inspected. Recent studies have demonstrated an inverse relationship between flow velocity and cilia length, zeta potential, and Helmholtz-Smoluchowski velocity. The streamlines show that the growth of the trapping boluses is affected by several factors, including the nanoparticles' volume fraction, the cilia's length, the amplitude ratio, the eccentricity, and the zeta potential. These results not only shed light on how nanofluids move, but they also have potential applications in microfluidics, heat transfer, and biomedical engineering.

摘要

钴铁氧体纳米粒子具有独特的磁学特性,使其适用于生物成像和治疗应用。通过纤毛环了解纳米流体中的活性,可能会为磁共振成像提供更好的对比剂,并改善癌症治疗和其他医学治疗。本文对通过电渗流穿过纤毛环的纳米流体输运的理论结论进行了全面分析。该纳米流体由钴铁氧体纳米粒子(CoFeO)、水(HO)和乙二醇(CHO)组成。作为构建物理模型调查的一部分,基于质量、动量和能量守恒进行了数学分析。利用无量纲分析和数学约束条件来进一步了解该系统。通过生成微分方程并包括适当的边界条件,可以获得精确解,并可以进行可视化检查。最近的研究表明,流速与纤毛长度、zeta 电位和亥姆霍兹-斯莫卢霍夫斯基速度呈反比关系。流线表明,捕获小球的生长受到几个因素的影响,包括纳米粒子的体积分数、纤毛的长度、振幅比、偏心率和 zeta 电位。这些结果不仅揭示了纳米流体的运动方式,而且在微流控、传热和生物医学工程等领域具有潜在的应用。

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