Department of Physics , Muğla Sıtkı Koçman University , 48000 Muğla , Turkey.
ACS Appl Mater Interfaces. 2019 Feb 20;11(7):6858-6866. doi: 10.1021/acsami.8b22600. Epub 2019 Feb 7.
In this study, the ac magnetic hyperthermia responses of spinel CoFeO, MnFeO, and NiFeO nanoparticles of comparable sizes (∼20 nm) were investigated to evaluate their feasibility of use in magnetic hyperthermia. The heating ability of EDT-coated nanoparticles which were dispersed in two different carrier media, deionized water and ethylene glycol, at concentrations of 1 and 2 mg/mL, was evaluated by estimating the specific loss power (SLP) (which is a measure of magnetic energy transformed into heat) under magnetic fields of 15, 25, and 50 kA/m at a constant frequency of 195 kHz. The maximum value of SLP has been found to be ∼315 W/g for CoFeO and ∼295 W/g for MnFeO and NiFeO nanoparticles. We report very promising heating temperature rising characteristics of CoFeO, MnFeO, and NiFeO nanoparticles under different applied magnetic fields that indicate the effectiveness of these nanoparticles as hyperthermia agents.
在这项研究中，我们研究了具有相似尺寸（约 20nm）的尖晶石 CoFeO、MnFeO 和 NiFeO 纳米粒子的交流磁致热响应，以评估它们在磁致热疗中的应用可行性。我们通过在磁场强度为 15、25 和 50kA/m、恒定频率为 195kHz 的条件下，分别测量浓度为 1 和 2mg/mL 的 EDT 包覆纳米粒子在两种不同载体介质（去离子水和乙二醇）中的比损耗功率（SLP）（这是衡量磁能转化为热能的指标），评估了纳米粒子的加热能力。结果发现，CoFeO 纳米粒子的最大 SLP 值约为 315W/g，MnFeO 和 NiFeO 纳米粒子的最大 SLP 值约为 295W/g。我们报道了 CoFeO、MnFeO 和 NiFeO 纳米粒子在不同外加磁场下具有非常有前景的升温特性，这表明这些纳米粒子作为热疗剂的有效性。
