Enhanced activation of mechanistic target of rapamycin complex 1 signaling in eruptive xanthomas.
作者信息
Huang Yan, Cui Baiping, Bai Yun, Wang Juan, Dou Hanyu, Jin Yanfei, Du Qian, Lai Yongxian, Liu Yeqiang, Ding Xiaolei
机构信息
Institute of Geriatrics, Affiliated Nantong Hospital of Shanghai University (The Sixth People's Hospital of Nantong), School of Medicine, Shanghai University, Nantong, China.
Shanghai Engineering Research Center of Organ Repair, School of Medicine, Shanghai University, Shanghai, China.
出版信息
JAAD Int. 2023 Jul 21;13:26-27. doi: 10.1016/j.jdin.2023.07.001. eCollection 2023 Dec.
Abstract
摘要
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The regulation of skin homeostasis, repair and the pathogenesis of skin diseases by spatiotemporal activation of epidermal mTOR signaling.通过表皮mTOR信号的时空激活对皮肤稳态、修复及皮肤疾病发病机制的调节
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Eruptive xanthomas as a marker for metabolic disorders: A specific form of xanthoma that reflects hypertriglyceridemia.发疹性黄瘤作为代谢紊乱的标志物：一种反映高甘油三酯血症的特殊黄瘤形式。
Clin Case Rep. 2022 Apr 21;10(4):e05671. doi: 10.1002/ccr3.5671. eCollection 2022 Apr.
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Lysosomal cholesterol activates mTORC1 via an SLC38A9-Niemann-Pick C1 signaling complex.溶酶体胆固醇通过SLC38A9-尼曼-皮克病C1型信号复合物激活mTORC1。
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