Wagh Mahendra A, Shinde Dinesh R, Gamidi Rama Krishna, Sanjayan Gangadhar J
Organic Chemistry Division, CSIR-National Chemical Laboratory (CSIR-NCL), Dr. Homi Bhabha Road, Pune-411008, India.
Academy of Scientific and Innovative research (AcSIR), Sector 19, Kamla Nehru Nagar, Ghaziabad, Uttar Pradesh-201002, India.
Org Biomol Chem. 2023 Aug 30;21(34):6914-6918. doi: 10.1039/d3ob01174g.
This communication reports a nature-inspired Janus G-C nucleobase featuring two recognition sites: DDA (G mimic) and DAA (C mimic), which is capable of forming a linear tape-like supramolecular polymer structure. As demonstrated herein, the amino group of this self-assembling system can be further modified to yield a highly stable quadruple H-bonding system as well as a masked self-assembling system cleavable upon exposure to light.
本通讯报道了一种受自然启发的Janus G-C核碱基，其具有两个识别位点：DDA（G模拟物）和DAA（C模拟物），能够形成线性带状超分子聚合物结构。如本文所示，该自组装系统的氨基可进一步修饰，以产生高度稳定的四重氢键系统以及在光照下可裂解的掩蔽自组装系统。
