Department of Psychiatry, University of California Los Angeles, Center for Sleep Research, 16111 Plummer St, North Hills, Los Angeles, CA, 91343, USA.
A.N. Severtsov Institute of Ecology and Evolution, Moscow, Russia.
J Comp Physiol B. 2024 Jun;194(3):315-333. doi: 10.1007/s00360-023-01511-7. Epub 2023 Aug 18.
While the majority of studies have concluded that sleep deprivation causes detrimental effects on various cognitive processes, some studies reported conflicting results. We examined the effects of a 108-h total sleep deprivation (TSD) on working memory in the northern fur seal, an animal with unusual sleep phenomenology and long-range annual migrations. The performance of fur seals was evaluated in a two-choice visual delayed matching to sample (DMTS) task, which is commonly used to evaluate working memory. In baseline conditions, the performance of fur seals in a DMTS task based on the percentage of errors was somewhat comparable with that in nonhuman primates at similar delays. We have determined that a 108-h TSD did not affect fur seals' performance in a visual DMTS task as measured by overall percentage of errors and response latencies. On the contrary, all fur seals improved task performance over the study, including the baseline, TSD and recovery conditions. In addition, TSD did not change the direction and strength of the pattern of behavioral lateralization in fur seals. We conclude that a 108-h TSD did not interfere with working memory in a DMTS test in northern fur seals.
虽然大多数研究得出结论，睡眠剥夺对各种认知过程都有不利影响，但也有一些研究报告了相互矛盾的结果。我们研究了为期 108 小时的总睡眠剥夺（TSD）对北方海狗的工作记忆的影响，北方海狗具有不寻常的睡眠现象和长途年度迁徙。通过二选一视觉延迟匹配样本（DMTS）任务评估海狗的表现，该任务常用于评估工作记忆。在基线条件下，基于错误百分比的 DMTS 任务中，海狗的表现与类似延迟的非人类灵长类动物相当。我们已经确定，108 小时的 TSD 不会影响海狗在视觉 DMTS 任务中的表现，这可以通过总错误百分比和反应时来衡量。相反，所有海狗在整个研究过程中，包括基线、TSD 和恢复条件下，都提高了任务表现。此外，TSD 并没有改变海狗行为侧化模式的方向和强度。我们的结论是，108 小时的 TSD 不会干扰北方海狗 DMTS 测试中的工作记忆。
