• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

The potential impact of clinical factors on blood-based biomarkers for Alzheimer's disease.

作者信息

Pan Fengfeng, Lu Yan, Huang Qi, Xie Fang, Yang Jingye, Guo Qihao

机构信息

Department of Gerontology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.

PET Center, Huashan Hospital, Fudan University, Shanghai, 200233, China.

出版信息

Transl Neurodegener. 2023 Aug 18;12(1):39. doi: 10.1186/s40035-023-00371-z.

DOI:10.1186/s40035-023-00371-z
PMID:37596644
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10436434/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f995/10436434/ab390394dc8d/40035_2023_371_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f995/10436434/ab390394dc8d/40035_2023_371_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f995/10436434/ab390394dc8d/40035_2023_371_Fig1_HTML.jpg

相似文献

1
The potential impact of clinical factors on blood-based biomarkers for Alzheimer's disease.临床因素对阿尔茨海默病血液生物标志物的潜在影响。
Transl Neurodegener. 2023 Aug 18;12(1):39. doi: 10.1186/s40035-023-00371-z.
2
Research criteria for the diagnosis of Alzheimer's disease: genetic risk factors, blood biomarkers and olfactory dysfunction.阿尔茨海默病诊断的研究标准:遗传风险因素、血液生物标志物与嗅觉功能障碍。
Int Psychogeriatr. 2008 Aug;20(4):853-5. doi: 10.1017/S1041610208006807. Epub 2008 Apr 17.
3
The ROSAS Cohort: A Prospective, Longitudinal Study of Biomarkers for Alzheimer's Disease. Strategy, Methods and Initial Results.ROSAS 队列:阿尔茨海默病生物标志物的前瞻性纵向研究。策略、方法和初步结果。
J Prev Alzheimers Dis. 2017;4(3):183-193. doi: 10.14283/jpad.2017.8.
4
Alzheimer's disease.阿尔茨海默病。
Lancet. 2011 Mar 19;377(9770):1019-31. doi: 10.1016/S0140-6736(10)61349-9. Epub 2011 Mar 1.
5
Alzheimer's disease biomarkers: their value in diagnosis and clinical trials.阿尔茨海默病生物标志物:它们在诊断和临床试验中的价值。
Front Biosci. 2002 Apr 1;7:d986-8. doi: 10.2741/A824.
6
Blood-based biomarkers of Alzheimer's disease: challenging but feasible.阿尔茨海默病的血液生物标志物:具有挑战性但可行。
Biomark Med. 2010 Feb;4(1):65-79. doi: 10.2217/bmm.09.84.
7
Amyloid beta protein in plasma as a diagnostic marker for Alzheimer's disease.血浆中的β淀粉样蛋白作为阿尔茨海默病的诊断标志物。
Neurobiol Aging. 1998 Mar-Apr;19(2):161-3. doi: 10.1016/s0197-4580(98)00015-3.
8
Platelets, lymphocytes and erythrocytes from Alzheimer's disease patients: the quest for blood cell-based biomarkers.阿尔茨海默病患者的血小板、淋巴细胞和红细胞:寻找基于血细胞的生物标志物。
Folia Neuropathol. 2018;56(1):14-20. doi: 10.5114/fn.2018.74655.
9
Blood-based biomarkers for Alzheimer's disease: plasma Aβ40 and Aβ42, and genetic variants.用于阿尔茨海默病的基于血液的生物标志物:血浆 Aβ40 和 Aβ42 以及遗传变异。
Neurobiol Aging. 2011 Dec;32 Suppl 1(Suppl 1):S10-9. doi: 10.1016/j.neurobiolaging.2011.09.004.
10
Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts.血液磷酸化 tau 181 作为阿尔茨海默病的生物标志物:使用来自四个前瞻性队列的数据进行的诊断性能和预测模型研究。
Lancet Neurol. 2020 May;19(5):422-433. doi: 10.1016/S1474-4422(20)30071-5.

引用本文的文献

1
Impact of Manganese on Neuronal Function: An Exploratory Multi-Omics Study on Ferroalloy Workers in Brescia, Italy.锰对神经元功能的影响:意大利布雷西亚铁合金工人的探索性多组学研究
Brain Sci. 2025 Jul 31;15(8):829. doi: 10.3390/brainsci15080829.
2
Associations of Plasma p-tau181 With Age, Adjusted for Kidney Function and Sociodemographic Factors.血浆p-tau181与年龄的关联,经肾功能和社会人口学因素校正。
Int J Geriatr Psychiatry. 2025 Aug;40(8):e70138. doi: 10.1002/gps.70138.
3
Effects of obesity on plasma biomarker and amyloid PET trajectories in Alzheimer's disease.

本文引用的文献

1
Cross-sectional and longitudinal association of sleep and Alzheimer biomarkers in cognitively unimpaired adults.认知未受损成年人睡眠与阿尔茨海默病生物标志物的横断面及纵向关联
Brain Commun. 2022 Nov 3;4(6):fcac257. doi: 10.1093/braincomms/fcac257. eCollection 2022.
2
Performance of plasma phosphorylated tau 181 and 217 in the community.社区人群中血浆磷酸化 tau181 和 tau217 的检测性能。
Nat Med. 2022 Jul;28(7):1398-1405. doi: 10.1038/s41591-022-01822-2. Epub 2022 May 26.
3
Blood-based biomarkers for Alzheimer's disease: towards clinical implementation.
肥胖对阿尔茨海默病血浆生物标志物及淀粉样蛋白PET轨迹的影响。
Alzheimers Dement (Amst). 2025 Jul 3;17(3):e70143. doi: 10.1002/dad2.70143. eCollection 2025 Jul-Sep.
4
Heritability of Alzheimer-related plasma biomarkers in the Amish population.阿米什人群中阿尔茨海默病相关血浆生物标志物的遗传力。
medRxiv. 2025 May 21:2025.05.13.25327557. doi: 10.1101/2025.05.13.25327557.
5
Impact of Manganese on Neuronal Function: An Exploratory MultiOmic Study on Ferroalloy Workers in Brescia, Italy.锰对神经元功能的影响:意大利布雷西亚铁合金工人的一项探索性多组学研究。
medRxiv. 2025 May 6:2025.05.02.25326824. doi: 10.1101/2025.05.02.25326824.
6
Relating the molecular phenotype of ulcerative colitis to the clinical course.将溃疡性结肠炎的分子表型与临床病程相关联。
Sci Rep. 2025 Mar 11;15(1):8342. doi: 10.1038/s41598-025-90618-8.
7
Plasma biomarkers for diagnosis and differentiation and their cognitive correlations in patients with Alzheimer's disease.阿尔茨海默病患者诊断与鉴别诊断的血浆生物标志物及其认知相关性
Brain Commun. 2025 Feb 25;7(2):fcaf094. doi: 10.1093/braincomms/fcaf094. eCollection 2025.
8
Disentangling relationships between Alzheimer's disease plasma biomarkers and established biomarkers in patients of tertiary memory clinics.理清三级记忆诊所患者中阿尔茨海默病血浆生物标志物与既定生物标志物之间的关系。
EBioMedicine. 2025 Feb;112:105504. doi: 10.1016/j.ebiom.2024.105504. Epub 2024 Dec 18.
9
How well do plasma Alzheimer's disease biomarkers reflect the CSF amyloid status?血浆阿尔茨海默病生物标志物在多大程度上反映脑脊液淀粉样蛋白状态?
J Neurol Neurosurg Psychiatry. 2025 May 14;96(6):566-572. doi: 10.1136/jnnp-2024-334122.
10
Neuroimaging and biofluid biomarkers across race and ethnicity in older adults across the spectrum of cognition.神经影像学和生物流体生物标志物在认知谱中老年人群体中的种族和民族差异。
Ageing Res Rev. 2024 Nov;101:102507. doi: 10.1016/j.arr.2024.102507. Epub 2024 Sep 19.
用于阿尔茨海默病的血液生物标志物:迈向临床应用
Lancet Neurol. 2022 Jan;21(1):66-77. doi: 10.1016/S1474-4422(21)00361-6. Epub 2021 Nov 24.
4
Associations of amyloid and neurodegeneration plasma biomarkers with comorbidities.淀粉样蛋白和神经退行性变血浆生物标志物与共病的关联。
Alzheimers Dement. 2022 Jun;18(6):1128-1140. doi: 10.1002/alz.12466. Epub 2021 Sep 27.
5
Plasma P-tau181 to Aβ42 ratio is associated with brain amyloid burden and hippocampal atrophy in an Asian cohort of Alzheimer's disease patients with concomitant cerebrovascular disease.血浆 P-tau181 与 Aβ42 比值与伴有脑血管病的亚洲阿尔茨海默病患者的脑淀粉样蛋白负荷和海马萎缩相关。
Alzheimers Dement. 2021 Oct;17(10):1649-1662. doi: 10.1002/alz.12332. Epub 2021 Mar 31.
6
Plasma p-tau181, p-tau217, and other blood-based Alzheimer's disease biomarkers in a multi-ethnic, community study.多民族社区研究中的血浆 p-tau181、p-tau217 和其他基于血液的阿尔茨海默病生物标志物。
Alzheimers Dement. 2021 Aug;17(8):1353-1364. doi: 10.1002/alz.12301. Epub 2021 Feb 13.
7
From Brain to Heart: Possible Role of Amyloid-β in Ischemic Heart Disease and Ischemia-Reperfusion Injury.从脑到心:β淀粉样蛋白在缺血性心脏病和缺血再灌注损伤中的可能作用。
Int J Mol Sci. 2020 Dec 17;21(24):9655. doi: 10.3390/ijms21249655.
8
Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies.载脂蛋白 E 与阿尔茨海默病:发病机制与靶向治疗策略。
Nat Rev Neurol. 2019 Sep;15(9):501-518. doi: 10.1038/s41582-019-0228-7. Epub 2019 Jul 31.
9
Associations Between Hepatic Functions and Plasma Amyloid-Beta Levels-Implications for the Capacity of Liver in Peripheral Amyloid-Beta Clearance.肝功能与血浆β淀粉样蛋白水平之间的关联——对肝脏在外周β淀粉样蛋白清除能力方面的启示
Mol Neurobiol. 2017 Apr;54(3):2338-2344. doi: 10.1007/s12035-016-9826-1. Epub 2016 Mar 9.
10
Thyroid hormone regulates endogenous amyloid-beta precursor protein gene expression and processing in both in vitro and in vivo models.甲状腺激素在体外和体内模型中均调节内源性淀粉样前体蛋白基因的表达和加工。
Thyroid. 2006 Dec;16(12):1207-13. doi: 10.1089/thy.2006.16.1207.