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Human serum albumin-induced modification of Ton-B-dependent receptor expression in cefiderocol-exposed carbapenem-resistant Acinetobacter baumannii.

作者信息

Nishimura Brent, Escalante Jenny, Mezcord Vyanka, Tuttobene Marisel R, Subils Tomás, Actis Luis A, Pasteran Fernando, Tolmasky Marcelo E, Bonomo Robert A, Ramirez María Soledad

机构信息

Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA.

Área Biología Molecular, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Rosario, Argentina; Instituto de Biología Molecular y Celular de Rosario (IBR, CONICET-UNR), Rosario, Argentina.

出版信息

Int J Antimicrob Agents. 2023 Nov;62(5):106950. doi: 10.1016/j.ijantimicag.2023.106950. Epub 2023 Aug 18.

DOI:10.1016/j.ijantimicag.2023.106950
PMID:37597787
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11066775/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1055/11066775/d472e50721ed/nihms-1979981-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1055/11066775/d472e50721ed/nihms-1979981-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1055/11066775/d472e50721ed/nihms-1979981-f0001.jpg

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Human serum albumin-induced modification of Ton-B-dependent receptor expression in cefiderocol-exposed carbapenem-resistant Acinetobacter baumannii.人血清白蛋白诱导头孢地尔暴露的耐碳青霉烯鲍曼不动杆菌中Ton-B依赖性受体表达的改变
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2
Role of β-lactamase inhibitors on cefiderocol activity against carbapenem-resistant Acinetobacter species.β-内酰胺酶抑制剂对头孢地尔抗碳青霉烯类耐药不动杆菌属细菌活性的作用
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3
In vivo development of cefiderocol resistance in carbapenem-resistant Acinetobacter baumannii associated with the downregulation of a TonB-dependent siderophore receptor, PiuA.耐碳青霉烯鲍曼不动杆菌中头孢地尔耐药性的体内发展与一种依赖TonB的铁载体受体PiuA的下调有关。
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Prospective role of cefiderocol in the management of carbapenem-resistant Acinetobacter baumannii infections: Review of the evidence.头孢地尔在碳青霉烯类耐药鲍曼不动杆菌感染管理中的前瞻性作用：证据回顾。
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PLoS One. 2024 Jun 28;19(6):e0306273. doi: 10.1371/journal.pone.0306273. eCollection 2024.
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Insights into the activity of cefiderocol against PER-2 producing Enterobacterales.

本文引用的文献

1
The Iron Content of Human Serum Albumin Modulates the Susceptibility of to Cefiderocol.人血清白蛋白的铁含量调节对头孢地尔的敏感性。
Biomedicines. 2023 Feb 20;11(2):639. doi: 10.3390/biomedicines11020639.
2
Human Serum Proteins and Susceptibility of to Cefiderocol: Role of Iron Transport.人血清蛋白与对头孢地尔的敏感性：铁转运的作用
Biomedicines. 2022 Mar 3;10(3):600. doi: 10.3390/biomedicines10030600.
3
Interplay between Meropenem and Human Serum Albumin on Expression of Carbapenem Resistance Genes and Natural Competence in Acinetobacter baumannii.
对头孢地尔对产PER-2肠杆菌科细菌活性的见解。
Antimicrob Agents Chemother. 2024 Jun 5;68(6):e0172023. doi: 10.1128/aac.01720-23. Epub 2024 May 1.
美罗培南与人类血清白蛋白对鲍曼不动杆菌碳青霉烯耐药基因表达及自然感受态的相互作用
Antimicrob Agents Chemother. 2021 Sep 17;65(10):e0101921. doi: 10.1128/AAC.01019-21. Epub 2021 Jul 19.
4
Human Pleural Fluid Elicits Pyruvate and Phenylalanine Metabolism in to Enhance Cytotoxicity and Immune Evasion.人胸腔积液引发丙酮酸和苯丙氨酸代谢以增强细胞毒性和免疫逃逸。
Front Microbiol. 2019 Jul 17;10:1581. doi: 10.3389/fmicb.2019.01581. eCollection 2019.
5
AB5075, a Highly Virulent Isolate of Acinetobacter baumannii, as a Model Strain for the Evaluation of Pathogenesis and Antimicrobial Treatments.鲍曼不动杆菌高毒力菌株AB5075作为评估发病机制和抗菌治疗的模型菌株
mBio. 2014 May 27;5(3):e01076-14. doi: 10.1128/mBio.01076-14.
6
Analysis of antibiotic resistance genes in multidrug-resistant Acinetobacter sp. isolates from military and civilian patients treated at the Walter Reed Army Medical Center.对从沃尔特里德陆军医疗中心接受治疗的军事和 civilian 患者中分离出的多重耐药不动杆菌属菌株中的抗生素耐药基因进行分析。 注：这里“civilian”常见释义为“平民”“民用的”等，结合语境这里可能是指非军事人员的患者，翻译为“ civilian”更合适，但如果有更准确的背景信息，可能有更精准的译法。
Antimicrob Agents Chemother. 2006 Dec;50(12):4114-23. doi: 10.1128/AAC.00778-06. Epub 2006 Sep 25.