Geriatrics Department, The First People's Hospital of Lanzhou City, Lanzhou, Gansu, China.
The First People's Hospital of Lanzhou City, Lanzhou, Gansu, China.
Technol Health Care. 2024;32(3):1489-1502. doi: 10.3233/THC-230554.
It is recommended to use non-invasive positive pressure ventilation in elderly patients with heart failure combined with obstructive sleep apnea syndrome (OSAS).
To study the therapeutic effect of non-invasive positive pressure ventilation on elderly patients with heart failure complicated with OSAS.
Using the random number table method, 119 elderly patients with heart failure complicated with OSAS who were admitted to our hospital from April 2020 to April 2021 were divided into the observation (60 cases) and control (59 cases) groups. On the basis of conventional drug treatment, patients in the observation group were treated with non-invasive positive pressure ventilation, and patients in the control group were treated with low-flow oxygen inhalation. The sleep quality, hemoglobin, red blood cells, erythropoietin, pro-brain natriureticpeptide (pro-BNP) levels and blood pressure were compared.
After treatment, levels of hemoglobin, erythrocytes, erythropoietin, pro-BNP, blood pressure and sleep apnea-hypopnea index in the observation group were lower before treatment and in the control group in the same period. The oxygen saturation was higher before treatment and the control group in the same period (P< 0.05). The overall satisfaction with sleep quality in the observation group was higher (P< 0.05).
Non-invasive positive pressure ventilation can improve blood oxygen saturation and sleep quality in elderly patients with heart failure complicated with OSAS, and reduce pro-BNP level.
建议对合并阻塞性睡眠呼吸暂停低通气综合征（OSAS）的老年心力衰竭患者使用无创正压通气。
研究无创正压通气对老年心力衰竭合并 OSAS 患者的治疗效果。
采用随机数字表法，将 2020 年 4 月至 2021 年 4 月我院收治的 119 例老年心力衰竭合并 OSAS 患者分为观察组（60 例）和对照组（59 例）。在常规药物治疗的基础上，观察组患者采用无创正压通气治疗，对照组患者采用低流量吸氧治疗。比较两组患者的睡眠质量、血红蛋白、红细胞、红细胞生成素、脑利钠肽前体（pro-BNP）水平及血压。
治疗后，观察组血红蛋白、红细胞、红细胞生成素、pro-BNP、血压、睡眠呼吸暂停低通气指数均低于同组治疗前及同期对照组（P<0.05），观察组血氧饱和度高于同组治疗前及同期对照组（P<0.05）。观察组患者对睡眠质量的总体满意度高于对照组（P<0.05）。
无创正压通气可改善老年心力衰竭合并 OSAS 患者的血氧饱和度和睡眠质量，降低 pro-BNP 水平。
