Blood pressure pattern among blood donors exposed to SARS-CoV-2 in Luanda, Angola: A retrospective study.

BACKGROUND AND AIMS

SARS-CoV-2 infection is a public health concern. Several aspects related to the pattern of infection remain unclear. This study aimed to investigate the blood pressure pattern among blood donors exposed to SARS-CoV-2 in Luanda, Angola, a sub-Saharan African country.

METHODS

We performed a retrospective analysis containing 343 blood donors from December 2019 to September 2020. Parametric tests compared means while and logistic regression checked features associated with high blood pressure and were considered significant when  < 0.05.

RESULTS

The mean age of blood donors was 32.2 ± 8.81 years (ranging from 18 to 61 years) and 93% of the men's gender. Overall, 4.7% of the studied population had been exposed to SARS-CoV-2. High blood pressure prevalence increased from unexposed to exposed SARS-CoV-2 (6.7%-18.8%,  = 0.071). SARS-CoV-2 exposure increase systole (131 ± 12.2 mmHg to 136 ± 14.2 mmHg,  = 0.098), diastole (79.9 ± 9.53 mmHg to 84.2 ± 12.7 mmHg,  = 0.086), pulse in beats per minute (72.0 ± 11.1 to 73.7 ± 8.50,  = 0.553), and decrease donating time (6.31 ± 3.72 min to 5.48 ± 1.61 min,  = 0.371). Chances of having high blood pressure were high [OR: 3.20 (95% confidence interval [CI]: 0.85-12.1),  = 0.086] in exposed SARS-CoV-2. Donors exposed to SARS-CoV-2 with abnormal donation time increased from the donor up to 40 years to over 40 years (from 35.7% to 50%,  = 0.696). The mean systolic, diastolic, and pulse pressure were higher for non-O donors ( > 0.05). A significant link was observed, between the Rhesus factor and blood pressure status ( = 0.032).

CONCLUSION

We showed important variations in blood pressure indices of the Angolan population exposed to SARS-CoV-2. Older age and non-O blood groups appear to be important biological factors for SARS-CoV-2 infection, as well as the risk of developing cardiovascular disease after or during SARS-CoV-2 exposure. Further studies assessing the impact on cardiovascular functions with ongoing or long-term SARS-CoV-2 exposure in individuals from resource-limited countries should be considered.