Wang Genghuan, Lin Yingcong, Shen Heping, Wang Yifei, Chu Wen Lai
Department of Neurosurgery, The Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang 314000, P.R. China.
Department of Neurosurgery, Zhejiang Chinese Medicine University, Hongzhou, Zhejiang 310053, P.R. China.
Oncol Lett. 2023 Jul 31;26(3):402. doi: 10.3892/ol.2023.13987. eCollection 2023 Sep.
Intracranial Rosai-Dorfman disease (RDD) is a rare, self-limiting histiocytic disease of unknown etiology. Extranodal marginal zone lymphoma of the mucosa-associated lymphoid tissue (MALT lymphoma) is also rare and intracranial RDD complicated by MALT lymphoma is even rarer. The present study reports a case of a 55-year-old female who was admitted to The Second Affiliated Hospital of Jiaxing University (Jiaxing, China) with headache for half a month and ptosis of the right eyelid for 4 days. Computerised tomography and magnetic resonance imaging revealed a right parasellar tumor and, subsequently, subtotal resection of the tumor was performed. Postoperative pathology revealed intracranial RDD complicated by MALT lymphoma. The patient received chemotherapy after surgery and achieved good therapeutic effects. After 12 months of follow-up, the residual tumor disappeared and the ptosis prominently improved. To the to the best of the authors' knowledge, the present case is the first reported case of an adult intracranial RDD complicated by MALT lymphoma.
颅内罗萨伊-多夫曼病（RDD）是一种病因不明的罕见的自限性组织细胞疾病。黏膜相关淋巴组织结外边缘区淋巴瘤（MALT淋巴瘤）也很罕见，而并发MALT淋巴瘤的颅内RDD更为罕见。本研究报告了一例55岁女性患者，因头痛半月、右眼睑下垂4天入住嘉兴学院附属第二医院（中国嘉兴）。计算机断层扫描和磁共振成像显示右侧鞍旁肿瘤，随后进行了肿瘤次全切除。术后病理显示颅内RDD并发MALT淋巴瘤。患者术后接受化疗，取得了良好的治疗效果。经过12个月的随访，残留肿瘤消失，眼睑下垂明显改善。据作者所知，本病例是首例报道的成人颅内RDD并发MALT淋巴瘤的病例。
