中脑原发性黏膜相关淋巴组织淋巴瘤：一例报告

Primary mucosa-associated lymphoid tissue lymphoma in the midbrain: A case report.

作者信息

Zhao Yong-Rui, Hu Rong-Hua, Wu Rui, Xu Jian-Kun

机构信息

Department of Radiation Oncology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.

Department of Hematology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.

出版信息

World J Clin Cases. 2021 Aug 6;9(22):6566-6574. doi: 10.12998/wjcc.v9.i22.6566.

DOI:10.12998/wjcc.v9.i22.6566

PMID:34435027

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8362552/

Abstract

BACKGROUND

Primary non-dural central nervous system mucosa-associated lymphoid tissue (MALT) lymphoma is a rare indolent B-cell lymphoma, with only a few reported cases worldwide.

CASE SUMMARY

A 33-year-old man presented with a 5-mo history of left blepharoptosis and a 4-mo history of right limb numbness and weakness. Magnetic resonance imaging showed a significantly enhanced mass in the left midbrain. Subsequent positron emission tomography revealed that the lesion had increased glucose uptake. A stereotactic robotic biopsy supported a diagnosis of MALT lymphoma. Then he was treated with radiation therapy (30Gy/15F), which resulted in complete remission. We also review the literature on brain parenchymal-based MALT lymphoma, including the clinical presentation, treatment options, and outcomes.

CONCLUSION

Although there is no consensus on the optimal treatment for this rare disease, patients can respond well when treated with radiotherapy alone.

摘要

背景

原发性非硬脑膜中枢神经系统黏膜相关淋巴组织（MALT）淋巴瘤是一种罕见的惰性B细胞淋巴瘤，全球仅有少数病例报道。

病例摘要

一名33岁男性，有5个月的左眼睑下垂病史和4个月的右肢麻木及无力病史。磁共振成像显示左中脑有一个明显强化的肿块。随后的正电子发射断层扫描显示该病变葡萄糖摄取增加。立体定向机器人活检支持MALT淋巴瘤的诊断。然后他接受了放射治疗（30Gy/15F），结果完全缓解。我们还回顾了关于脑实质型MALT淋巴瘤的文献，包括临床表现、治疗选择和结果。