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本文引用的文献

1
Third trimester stillbirth during the first wave of the SARS-CoV-2 pandemic: Similar rates with increase in placental vasculopathic pathology.SARS-CoV-2 大流行第一波期间的孕晚期死胎：胎盘血管病变病理增加，发生率相似。
Placenta. 2021 Jun;109:72-74. doi: 10.1016/j.placenta.2021.04.003. Epub 2021 Apr 19.
2
Intrauterine vertical SARS-CoV-2 infection: a case confirming transplacental transmission followed by divergence of the viral genome.宫内垂直 SARS-CoV-2 感染：一例证实胎盘传播后病毒基因组发生分歧的病例。
BJOG. 2021 Jul;128(8):1388-1394. doi: 10.1111/1471-0528.16682. Epub 2021 Mar 22.
3
Pregnancy and Breastfeeding During COVID-19 Pandemic: A Systematic Review of Published Pregnancy Cases.COVID-19 大流行期间的妊娠和哺乳：已发表妊娠病例的系统评价。
Front Public Health. 2020 Nov 23;8:558144. doi: 10.3389/fpubh.2020.558144. eCollection 2020.
4
Update: Characteristics of Symptomatic Women of Reproductive Age with Laboratory-Confirmed SARS-CoV-2 Infection by Pregnancy Status - United States, January 22-October 3, 2020.更新：2020 年 1 月 22 日至 10 月 3 日，美国按妊娠状况划分的有症状育龄期女性中经实验室确认感染 SARS-CoV-2 的特征。
MMWR Morb Mortal Wkly Rep. 2020 Nov 6;69(44):1641-1647. doi: 10.15585/mmwr.mm6944e3.
5
Coronavirus disease 2019 infection and placental histopathology in women delivering at term.2019 年冠状病毒病感染与足月分娩产妇的胎盘组织病理学。
Am J Obstet Gynecol. 2021 Apr;224(4):382.e1-382.e18. doi: 10.1016/j.ajog.2020.10.020. Epub 2020 Oct 19.
6
Pregnancy worsens the morbidity of COVID-19 and this effect becomes more prominent as pregnancy advances.怀孕会加重新冠病毒感染疾病（COVID-19）的发病率，且随着孕期进展，这种影响会更加显著。
Turk J Obstet Gynecol. 2020 Sep;17(3):149-154. doi: 10.4274/tjod.galenos.2020.38924. Epub 2020 Oct 2.
7
Vertical transmission of SARS CoV-2: a systematic review.SARS CoV-2 的垂直传播：系统评价。
J Matern Fetal Neonatal Med. 2022 Jul;35(14):2655-2662. doi: 10.1080/14767058.2020.1793322. Epub 2020 Jul 21.
8
Placental Pathology in COVID-19.COVID-19 相关的胎盘病理学
Am J Clin Pathol. 2020 Jun 8;154(1):23-32. doi: 10.1093/ajcp/aqaa089.
9
Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2: A Systematic Review.严重急性呼吸综合征冠状病毒2的垂直传播：一项系统综述
Am J Perinatol. 2020 Aug;37(10):1055-1060. doi: 10.1055/s-0040-1712161. Epub 2020 May 13.
10
Placental Pathology in Covid-19 Positive Mothers: Preliminary Findings.新冠病毒检测呈阳性的母亲的胎盘病理学：初步研究结果。
Pediatr Dev Pathol. 2020 May-Jun;23(3):177-180. doi: 10.1177/1093526620925569.

新冠病毒检测呈阳性的母亲所产胎盘的病理学检查：一则简短通讯

Pathological Examination of the Placenta in COVID-19-Positive Mothers: A Short Communication.

作者信息

Hantoushzadeh Sedigheh, Saeednejad Roya, Shariat Mamak, Moradi Raheleh

机构信息

Maternal, Fetal and Neonatal Research Center, Institute of Family Health, Tehran University of Medical Sciences, Tehran, Iran.

Breastfeeding Research Center, Institute of Family Health, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Iran J Pathol. 2023 Spring;18(2):217-220. doi: 10.30699/IJP.2023.551018.2860. Epub 2023 Jun 20.

DOI:10.30699/IJP.2023.551018.2860
PMID:37600569
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10439745/
Abstract

BACKGROUND & OBJECTIVE: It was declared that COVID-19 might be more severe in symptomatic pregnant patients. This study was conducted to examine the pathological indices of the placenta in pregnant women who were diagnosed with COVID-19.

METHODS

A total of 20 COVID-19-positive mothers were enrolled in this study. Detailed placental pathology findings were compared between subjects based on the history of abortion or occurrence of preterm delivery, hypertension, and diabetes.

RESULTS AND CONCLUSION

Intervillositis was the most frequent abnormality of the placenta. There was also a significant association between abortion history and maternal vascular malperfusion (MVM; =0.02). The placental abnormalities were found to be increased in women with COVID-19, regardless of maternal comorbidities. Further studies are needed to compare the placental pathology between COVID-19-positive women and healthy women.

摘要

背景与目的

据宣称，有症状的孕妇感染新冠病毒疾病（COVID-19）可能病情更严重。本研究旨在检查确诊感染COVID-19的孕妇胎盘的病理指标。

方法

本研究共纳入20名COVID-19呈阳性的母亲。根据流产史或早产、高血压和糖尿病的发生情况，对受试者之间详细的胎盘病理结果进行比较。

结果与结论

绒毛间炎是最常见的胎盘异常。流产史与母体血管灌注不良（MVM；P=0.02）之间也存在显著关联。无论孕产妇有无合并症，感染COVID-19的女性胎盘异常情况均有所增加。需要进一步研究来比较COVID-19呈阳性女性与健康女性的胎盘病理情况。