新冠病毒检测呈阳性的母亲所产胎盘的病理学检查：一则简短通讯
Pathological Examination of the Placenta in COVID-19-Positive Mothers: A Short Communication.
作者信息
Hantoushzadeh Sedigheh, Saeednejad Roya, Shariat Mamak, Moradi Raheleh
机构信息
Maternal, Fetal and Neonatal Research Center, Institute of Family Health, Tehran University of Medical Sciences, Tehran, Iran.
Breastfeeding Research Center, Institute of Family Health, Tehran University of Medical Sciences, Tehran, Iran.
出版信息
Iran J Pathol. 2023 Spring;18(2):217-220. doi: 10.30699/IJP.2023.551018.2860. Epub 2023 Jun 20.
BACKGROUND & OBJECTIVE: It was declared that COVID-19 might be more severe in symptomatic pregnant patients. This study was conducted to examine the pathological indices of the placenta in pregnant women who were diagnosed with COVID-19.
METHODS
A total of 20 COVID-19-positive mothers were enrolled in this study. Detailed placental pathology findings were compared between subjects based on the history of abortion or occurrence of preterm delivery, hypertension, and diabetes.
RESULTS AND CONCLUSION
Intervillositis was the most frequent abnormality of the placenta. There was also a significant association between abortion history and maternal vascular malperfusion (MVM; =0.02). The placental abnormalities were found to be increased in women with COVID-19, regardless of maternal comorbidities. Further studies are needed to compare the placental pathology between COVID-19-positive women and healthy women.
背景与目的
据宣称，有症状的孕妇感染新冠病毒疾病（COVID-19）可能病情更严重。本研究旨在检查确诊感染COVID-19的孕妇胎盘的病理指标。
方法
本研究共纳入20名COVID-19呈阳性的母亲。根据流产史或早产、高血压和糖尿病的发生情况，对受试者之间详细的胎盘病理结果进行比较。
结果与结论
绒毛间炎是最常见的胎盘异常。流产史与母体血管灌注不良（MVM；P=0.02）之间也存在显著关联。无论孕产妇有无合并症，感染COVID-19的女性胎盘异常情况均有所增加。需要进一步研究来比较COVID-19呈阳性女性与健康女性的胎盘病理情况。
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