Paulsamy Premalatha, Venkatesan Krishnaraju, Hamoud Alshahrani Shadia, Hamed Mohamed Ali Maha, Prabahar Kousalya, Prabhu Veeramani Vinoth, Khalil Elfaki Nahid, Elsayed Ahmed Rasha, Ahmed Elsayes Hala, Hussein Ahmed Abdalla Yahya, Babiker Osmsn Mohammed Osman, Ahmed Qureshi Absar, Alqahtani Friyal, Shaik Alavudeen Sirajudeen
College of Nursing, Mahala Branch for Girls, King Khalid University, Asir, Saudi Arabia.
Department of Pharmacology, College of Pharmacy, King Khalid University, Abha, Asir, Saudi Arabia.
Saudi Pharm J. 2023 Sep;31(9):101712. doi: 10.1016/j.jsps.2023.101712. Epub 2023 Aug 2.
The study sought to identify parental trends in children's self-medication, health-seeking behavior, knowledge of self-medication, antibiotic use, and antimicrobial resistance in Asir, Saudi Arabia.
A web-based cross-sectional study was carried out by a survey questionnaire. Snow Ball sampling technique was used to select the Eight hundred and sixteen parents with children in the Asir region by WhatsApp and email, and 650 participants who met the inclusion criteria consented to participate in the study.
There were 1809 episodes of childhood illnesses reported during the study period. The mean scores are on knowledge at 8.11 ± 2.43, favorable attitude at 17.60 ± 1.17, and practice was 7.72 ± 1.72, and a significant correlation was found between knowledge, attitude, and practice (KAP) at = 0.01. Out of 624, the majority of parents showed strong knowledge and proficiency in antibiotics. However, the attitude scores of over 50% towards the usage of antibiotics were subpar. Around 54% of parents were self-medicating their children and 43% were unaware that skipping doses contributes to anti-microbial resistance (AMR). The facilitators for self-medication were male gender (aOR: 2.13; 95% CI: 1.26-3.98, < 0.05), having more children (aOR: 2.78; 95% CI: 1.27-4.12 0.01), professional qualification (aOR:3.07; 95% CI 1.57- 4.68; 0.01), residing in urban area (aOR: 3.17; 95% CI: 2.13-5.61, < 0.05), working in health care (aOR: 5.99; 95% CI: 1.78-18.2, < 0.01) and high income (aOR: 3.57; 95% CI: 2.08-6.34, < 0.05).
The findings indicated that the majority of parents had unfavorable views and improper practices of antibiotic usage. Strategic education programs to the targeted population, especially to the parents about side effects of antibiotics, dangerous consequences of self-medication, and crucial AMR concerns must be addressed immediately.
本研究旨在确定沙特阿拉伯阿西尔地区家长在儿童自我用药、寻求医疗行为、自我用药知识、抗生素使用及抗菌药物耐药性方面的趋势。
通过调查问卷开展一项基于网络的横断面研究。采用滚雪球抽样技术，通过WhatsApp和电子邮件在阿西尔地区选取了816名有孩子的家长，650名符合纳入标准的参与者同意参与研究。
研究期间共报告了1809例儿童疾病。知识平均得分为8.11±2.43，积极态度平均得分为17.60±1.17，实践平均得分为7.72±1.72，知识、态度和实践（KAP）之间在α=0.01时存在显著相关性。在624名家长中，大多数家长对抗生素有较强的知识和熟练度。然而，超过50%的家长对抗生素使用的态度得分欠佳。约54%的家长给孩子自行用药，43%的家长不知道漏服剂量会导致抗菌药物耐药性（AMR）。自我用药的促进因素包括男性（调整后比值比：2.13；95%置信区间：1.26 - 3.98，P<0.05）、孩子较多（调整后比值比：2.78；95%置信区间：1.27 - 4.12，P<0.01）、专业资格（调整后比值比：3.07；95%置信区间1.57 - 4.68；P<0.01）、居住在城市地区（调整后比值比：3.17；95%置信区间：2.13 - 5.61，P<0.05）、从事医疗保健工作（调整后比值比：5.99；95%置信区间：1.78 - 18.2，P<\0.01）和高收入（调整后比值比：3.57；95%置信区间：2.08 - 6.34，P<0.05）。
研究结果表明，大多数家长对抗生素使用的观点不佳且做法不当。必须立即针对目标人群，特别是家长开展战略教育项目，内容包括抗生素的副作用、自我用药的危险后果以及关键的AMR问题。
