Treciokiene Indre, Peceliuniene Jurate, Wettermark Bjorn, Gulbinovic Jolanta, Taxis Katja
Department of PharmacoTherapy, -Epidemiology & -Economics, Faculty of Science and Engineering, University of Groningen, Antonius Deusinglaan 1, 9713, AV, Groningen, Netherlands.
Pharmacy and Pharmacology center, Institute of Biomedical Science, Faculty of Medicine, Vilnius University, M. K. Ciurlionio str.21, 03101 Vilnius, Lithuania.
Explor Res Clin Soc Pharm. 2023 Jul 24;11:100313. doi: 10.1016/j.rcsop.2023.100313. eCollection 2023 Sep.
Arterial hypertension is a lifelong disease, which management is recognized as the most effective way to reduce cardiovascular mortality. Even though there is extensive evidence on the benefits of lifestyle modification and antihypertensive treatment, many patients with hypertension do not reach blood pressure targets. This paper aims to review the history of antihypertensive treatment of one patient and identify the drug related problems that occurred over the study period. In this case report, the patient's health record was studied, guidelines checked and a semi-structured interview conducted. Drug related problems were identified and possible pharmacist interventions were introduced. Drug related problems that could have contributed to the lack of hypertension control were adherence, side effects and disease-drug interaction. Identified pharmacists' interventions ranged from managing self-medication, to collaboration with general practitioner to change prescribing, and counselling the patient on medication use, including adherence. Even though the drug related problems were not that serious in the studied case, the patient could have valued from pharmacist intervention.
动脉高血压是一种终身疾病，其管理被认为是降低心血管死亡率的最有效方法。尽管有大量证据表明生活方式改变和抗高血压治疗有益，但许多高血压患者并未达到血压目标。本文旨在回顾一名患者的抗高血压治疗史，并确定在研究期间出现的药物相关问题。在本病例报告中，研究了患者的健康记录，查阅了指南并进行了半结构化访谈。确定了药物相关问题，并介绍了可能的药剂师干预措施。可能导致高血压控制不佳的药物相关问题包括依从性、副作用和疾病-药物相互作用。确定的药剂师干预措施包括管理自我用药、与全科医生合作改变处方以及就药物使用（包括依从性）向患者提供咨询。尽管在所研究的病例中药物相关问题并不严重，但患者可能会从药剂师的干预中受益。
