Anesthetic management of super-selective intra-arterial Melphalan injection in an infant with retinoblastoma.

Intra-arterial Melphalan injection is an emerging treatment for children with advanced retinoblastoma. The procedure, which is frequently performed under general endotracheal anesthesia, can be complicated by technical difficulty and cardiorespiratory instability, which the anesthesiologist should be aware of. We describe the anesthetic management and special concerns during super-selective intra-arterial Melphalan injection in an infant with advanced retinoblastoma.