Su Zhu-Quan, Rao Wan-Yuan, Pan Xiao-Yi, Tang Jia-Xin, Fan Ming-Yue, Chen Xiao-Bo, Li Shi-Yue
State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China.
Infect Drug Resist. 2023 Aug 15;16:5329-5333. doi: 10.2147/IDR.S416483. eCollection 2023.
Disseminated infection caused by was seldom occurred. We reported a case of infection, presenting as multiple pulmonary cavities, thoracic wall abscess and vertebral destruction. The 37-year-old male had recurrent fever, chest wall swelling and pain, and lower limb numbness, he had weak physical condition and previously suffered from poorly controlled diabetes and severe periodontal disease for 3 years. Definite diagnosis of infection was made by metagenomic next‑generation sequencing (mNGS) in abscess drainage fluid. Systemic antibiotics and thoracic wall drainage were given, and the pulmonary cavity and the thoracic intermuscular abscess were significantly decreased. Few to no study reported the disseminated infection (pulmonary cavities, thoracic wall abscess and vertebral destruction) caused by . This case report highlighted the importance of mNGS for accurate diagnosis, as well as the timely drainage and antibiotics for effective treatment of infection.
由[病原体名称未给出]引起的播散性感染很少发生。我们报告了一例[病原体名称未给出]感染病例,表现为多个肺空洞、胸壁脓肿和椎体破坏。该37岁男性反复发热、胸壁肿胀疼痛及下肢麻木,身体状况较差,既往患糖尿病且控制不佳、重度牙周病3年。通过对脓肿引流液进行宏基因组下一代测序(mNGS)明确诊断为[病原体名称未给出]感染。给予全身抗生素治疗及胸壁引流,肺空洞和胸壁肌间脓肿明显缩小。很少有研究报道由[病原体名称未给出]引起的播散性感染(肺空洞、胸壁脓肿和椎体破坏)。本病例报告强调了mNGS对于准确诊断的重要性,以及及时引流和使用抗生素对[病原体名称未给出]感染进行有效治疗的重要性。