Zhu Xingxing, Chen Jialu, Wu Shengjie, Zeng Jiling, Sun Yahong, Wu Xiaohong
Department of Pulmonary and Critical Care Medicine, Haining People's Hospital, Haining, People's Republic of China.
Department of Gynaecology, Haining Maternal and Child Health Hospital, Haining, People's Republic of China.
Infect Drug Resist. 2024 Oct 16;17:4447-4454. doi: 10.2147/IDR.S490700. eCollection 2024.
The incidence of community-acquired empyema caused by the group (SAG) has been on the rise in the 2020s. To the best of our knowledge, while empyema caused individually by either strain has been reported, there are no reports on empyema caused by concurrent infection with these two strains. Here, we report for the first time empyema caused by concurrent infection with and (both SAG species) in a postoperative patient who had been treated for floor of the mouth carcinoma.
A 61-year-old male patient who had undergone surgical treatment for floor of the mouth carcinoma 2 year earlier suddenly presented with left-sided chest pain. Chest computed tomography (CT) revealed encapsulated pleural effusion on the left side, which was diagnosed as empyema. Metagenomic next-generation sequencing(mNGS) of the pleural fluid sample indicated mixed infection caused by and . The patient's condition improved about 5 weeks after treatment with thoracic fluid drainage and cephalosporin antibiotics.
This case highlights the possibility of concurrent infection with two SAG strains in patients with empyema. Currently, it is unclear whether there is a definitive relationship between a surgical history of carcinoma of the floor of the mouth and empyema caused by infection with SAG strains. This case could, perhaps, serve as a reference for future related research on the topic.
21世纪20年代，由唾液腺嗜二氧化碳噬纤维菌属（SAG）引起的社区获得性脓胸发病率呈上升趋势。据我们所知，虽然已有单独由这两种菌株之一引起脓胸的报道，但尚无关于这两种菌株同时感染导致脓胸的报道。在此，我们首次报告一例接受过口腔底癌治疗的术后患者，因同时感染嗜二氧化碳噬纤维菌属的两个菌种而导致脓胸。
一名61岁男性患者，2年前接受了口腔底癌手术治疗，突然出现左侧胸痛。胸部计算机断层扫描（CT）显示左侧有包裹性胸腔积液，诊断为脓胸。胸腔积液样本的宏基因组下一代测序（mNGS）表明由嗜二氧化碳噬纤维菌属的两个菌种混合感染所致。经胸腔引流和头孢菌素类抗生素治疗约5周后，患者病情好转。
本病例突出了脓胸患者同时感染两种唾液腺嗜二氧化碳噬纤维菌属菌株的可能性。目前尚不清楚口腔底癌手术史与唾液腺嗜二氧化碳噬纤维菌属菌株感染所致脓胸之间是否存在明确关联。本病例或许可为该主题未来的相关研究提供参考。
