Zhou Yue, Li Wei-Min, Fan Xiao-Fang, Huang Yan-Li, Gao Qi
Department of Ultrasonography, Affiliated Hospital of Jiangnan University, Wuxi, Jiangsu, People's Republic of China.
Department of Special Clinic, General Hospital of Eastern Theater Command, PLA, Nanjing, Jiangsu, People's Republic of China.
Int J Gen Med. 2023 Aug 14;16:3483-3490. doi: 10.2147/IJGM.S416403. eCollection 2023.
To explore the diagnostic value of positive features in the Chinese Thyroid Imaging Reporting and Data System (C-TIRADS) for thyroid nodules of different sizes.
A total of 1864 patients with 2347 thyroid nodules were selected from January 2021 to December 2022 and assessed according to C-TIRADS. According to the maximum diameter, nodules were divided into the A1 group (≤10 mm), A2 group (>10 mm,<20 mm), and A3 group (≥20 mm). With surgical pathology as the golden standard, the receiver operating characteristic curves (ROC) were constructed, and each group's area under the curve (AUC) was calculated. The diagnostic value of positive features in C-TIRADS for different sizes of thyroid nodules was analyzed.
In all groups, malignant thyroid nodules had a higher incidence of positive features than benign nodules (P < 0.05). In A1 group, the diagnostic efficiency of C-TIRADS positive features for thyroid nodules was vertical orientation> ill-defined/irregular margin or extrathyroidal extension> solid composition> markedly hypoechoic> microcalcifications. The AUCs were 0.718, 0.675, 0.609, 0.558, and 0.581, respectively. In A2 group, the diagnostic efficacy of each positive features for thyroid nodules was ill-defined/irregular margins or extra-thyroid invasion> solid composition> microcalcifications> markedly hypoechoic> vertical orientation. The AUCs were 0.854, 0.730, 0.719, 0.670, and 0.609, respectively. In A3 group, the diagnostic efficacy of each positive features for thyroid nodules was ill-defined/irregular margin or extrathyroidal extension> microcalcifications> solid composition> vertical orientation> markedly hypoechoic. The AUCs were 0.847, 0.778, 0.767, 0.584, and 0.560, respectively.
C-TIRADS positive features exhibited different diagnostic efficacy for thyroid nodules of various sizes, especially for thyroid nodules ≤10 mm, for which all positive features had low diagnostic efficacy.
探讨中国甲状腺影像报告和数据系统（C-TIRADS）中的阳性特征对不同大小甲状腺结节的诊断价值。
选取2021年1月至2022年12月期间共1864例患有2347个甲状腺结节的患者，并根据C-TIRADS进行评估。根据最大直径，结节被分为A1组（≤10mm）、A2组（>10mm，<20mm）和A3组（≥20mm）。以手术病理作为金标准，构建受试者操作特征曲线（ROC），并计算每组的曲线下面积（AUC）。分析C-TIRADS中阳性特征对不同大小甲状腺结节的诊断价值。
在所有组中，甲状腺恶性结节的阳性特征发生率高于良性结节（P<0.05）。在A1组中，C-TIRADS阳性特征对甲状腺结节的诊断效能为垂直位>边界不清/不规则或甲状腺外侵犯>实性成分>显著低回声>微钙化。AUC分别为0.718、0.675、0.609、0.558和0.581。在A2组中，各阳性特征对甲状腺结节的诊断效能为边界不清/不规则边缘或甲状腺外侵犯>实性成分>微钙化>显著低回声>垂直位。AUC分别为0.854、0.730、0.719、0.670和0.609。在A3组中，各阳性特征对甲状腺结节的诊断效能为边界不清/不规则边缘或甲状腺外侵犯>微钙化>实性成分>垂直位>显著低回声。AUC分别为0.847、0.778、0.767、0.584和0.560。
C-TIRADS阳性特征对不同大小的甲状腺结节表现出不同的诊断效能，尤其是对于≤10mm的甲状腺结节，所有阳性特征的诊断效能均较低。
