Wu Xuanxia, Zhou Mingming, Bu Juan, Chang Yuwen, Mahan Yeledan, Lu Huanhuan, Zhang Yanmin, Zhang Xiaoling, Wang Zhaoxia, Zhou Ling
Medical Research and Transformation Center, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People's Republic of China.
Health Management Center, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People's Republic of China.
Risk Manag Healthc Policy. 2023 Aug 14;16:1531-1544. doi: 10.2147/RMHP.S423794. eCollection 2023.
In this study, the aim was to investigate the prevalence and risk factors of hyperuricemia (HUA) in the urban health checkup population in Urumqi, Xinjiang, and thus provide clues for the prevention of HUA.
People who attended medical examinations from May 2021 to June 2022 at a hospital in Urumqi, Xinjiang, were selected for evaluation based on their general information, physical examination results, and laboratory test results. The chi-square test was used to determine whether there was a difference in the prevalence of HUA among participants with different characteristics. Using logistic regression analyses, risk factors for HUA were identified.
There were 8722 participants diagnosed with HUA, with an overall prevalence of 26.96%. The prevalence in men was 37.72%, significantly higher than in women (13.29%). Participants were characterized by a multiethnic composition, with Han (28.61%), Hui (27.88%) and Manchu (38.46%) being the three ethnicities with the highest prevalence. According to logistic regression analyses, HUA was associated with age, ethnicity, residence, marital status, body mass index (BMI), diastolic blood pressure (DBP), fasting blood glucose (FPG), triglyceride glucose (TyG) index, abdominal obesity, and dyslipidemia differently in males and females.
The prevalence of HUA was high in the urban health checkup population in Urumqi, Xinjiang, particularly among men and youth. The early intervention for HUA should be enhanced to reduce the risk of cardiovascular disease and other related conditions.
本研究旨在调查新疆乌鲁木齐市城市体检人群高尿酸血症(HUA)的患病率及危险因素,从而为HUA的预防提供线索。
选取2021年5月至2022年6月在新疆乌鲁木齐某医院参加体检的人员,根据其一般信息、体格检查结果和实验室检查结果进行评估。采用卡方检验确定不同特征参与者中HUA患病率是否存在差异。通过逻辑回归分析确定HUA的危险因素。
共有8722名参与者被诊断为HUA,总体患病率为26.96%。男性患病率为37.72%,显著高于女性(13.29%)。参与者具有多民族构成特征,汉族(28.61%)、回族(27.88%)和满族(38.46%)是患病率最高的三个民族。根据逻辑回归分析,HUA在男性和女性中与年龄、民族、居住地、婚姻状况、体重指数(BMI)、舒张压(DBP)、空腹血糖(FPG)、甘油三酯葡萄糖(TyG)指数、腹型肥胖和血脂异常的关联有所不同。
新疆乌鲁木齐市城市体检人群中HUA患病率较高,尤其是男性和年轻人。应加强对HUA的早期干预,以降低心血管疾病及其他相关疾病的风险。