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角膜盲与眼库:当前策略与最佳实践。

Corneal blindness and eye banking: Current strategies and best practices.

机构信息

Cornea and Refractive Services, Aravind Eye Hospital and Post Graduate Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India.

Cornea, Cataract and Refractive Surgery Services, Dr. R P Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Indian J Ophthalmol. 2023 Sep;71(9):3142-3148. doi: 10.4103/IJO.IJO_1942_23.

Abstract

Corneal blindness (CB) is one of the leading causes of blindness in India and globally, affecting around 8 million population worldwide. Many of these corneal blind patients may be visually rehabilitated by corneal transplantation (CT). Eye banking plays a crucial role in facilitating CT and ocular research. Many countries have adopted regulatory frameworks, quality assurance programs, and technological advancements to enhance the efficacy and safety of CT. Various infrastructural and organizational frameworks of eye banks (EBs) in India, according to the Eye Bank Association of India (EBAI), aid in establishing guidelines and standards for EB practices. Initiatives such as the National Programme for Control of Blindness (NPCB) have significantly contributed to eye donation rates and improved access to donor corneas. This review article discusses the established eye banking networks in countries such as India, the United States (USA), and Europe, where dedicated EB organizations work collaboratively to ensure efficient procurement, processing, and distribution of corneal tissue. It also highlights specific strategies employed in India and global countries to address EBs' challenges. These challenges include the shortage of donor corneas, improving donor screening and tissue processing techniques, ensuring timely distribution of corneal tissue, and maintaining high-quality standards. Interestingly, the comparative analysis between India and other developed countries highlights the similarities and differences in eye banking strategies. By understanding the strategies employed by different regions, EBs can learn from each other's experiences and work toward achieving optimal outcomes in CT and ocular research worldwide. It underscores the importance of knowledge sharing and collaborative efforts in addressing common challenges and implementing best practices in eye banking.

摘要

角膜盲症(CB)是印度和全球致盲的主要原因之一,全球约有 800 万人受到影响。许多这些角膜盲患者可以通过角膜移植(CT)来恢复视力。眼库在促进 CT 和眼部研究方面起着至关重要的作用。许多国家都采用了监管框架、质量保证计划和技术进步,以提高 CT 的效果和安全性。根据印度眼库协会(EBAI)的说法,印度的各种眼库(EB)基础设施和组织框架有助于为 EB 实践制定准则和标准。国家盲症控制计划(NPCB)等倡议极大地促进了眼捐赠率,并改善了对供体角膜的获取。本文讨论了印度、美国(USA)和欧洲等国家的既定眼库网络,在这些国家,专门的 EB 组织协作确保角膜组织的有效采购、处理和分配。它还强调了印度和全球国家为解决 EB 面临的挑战而采用的具体策略。这些挑战包括供体角膜短缺、改善供体筛选和组织处理技术、确保及时分配角膜组织以及保持高质量标准。有趣的是,印度与其他发达国家之间的比较分析突出了眼库策略的相似之处和不同之处。通过了解不同地区采用的策略,EB 可以相互学习经验,并努力在全球范围内实现 CT 和眼部研究的最佳效果。它强调了在处理共同挑战和实施眼库最佳实践方面分享知识和协作努力的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95e3/10565931/8453f0939080/IJO-71-3142-g001.jpg

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