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印度北部眼库的供体人口统计学特征及影响角膜利用的因素。

Donor demographics and factors affecting corneal utilisation in Eye Bank of North India.

机构信息

Department of Ophthalmology, Government Medical College and Hospital, Chandigarh, India.

Department of Ophthalmology AIIMS, Patna, Bihar, India.

出版信息

Int Ophthalmol. 2021 May;41(5):1773-1781. doi: 10.1007/s10792-021-01736-x. Epub 2021 Apr 24.

DOI:10.1007/s10792-021-01736-x
PMID:33893934
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8087588/
Abstract

INTRODUCTION

Nearly 6.8 million people in India have vision less than 6/60 in at least one eye due to corneal diseases; of these, about a million had bilateral involvement.

PURPOSE

To identify the challenges faced; the trends in collection, storage and utilisation of corneal tissues in an eye bank in north India.

MATERIALS AND METHODS

The past records of Eye Bank linked to a tertiary hospital in northern India were analysed from November'1999 to October'2015 with respect to number of eye donations per year, donor demographics and utilisation of corneal tissues.

RESULTS

The number of donations during the first 6 years were 100, 279 in the next 5 years and 473 in the last 5 years. The mean donor age was 63.2 ± 19.5 years. The percentage of donors less than 30, 31-60 and more than 60 years was 10%, 28% and 62%. Forty-two percent donations were from the hospital. The average time between the death and enucleation was 4.74 ± 5.31 hours. The percentage of corneas used in the donor age groups less than 30, 31-60 and above 60 years was 61.9%, 61.6% and 53.8%, respectively. The usability rate of the corneas from home and hospital was 63.7% and 55.3%, respectively.

CONCLUSIONS

The eye bank had a lukewarm response in the beginning, but gained momentum with time. The myths and beliefs prevalent in our society deter people from donating eyes freely. Each eye bank needs to individualise its problems and find solutions for adequate procurement and utilisation of tissue.

摘要

简介

印度约有 680 万人因角膜疾病导致至少一只眼视力低于 6/60,其中约有 100 万人双眼受累。

目的

确定印度北部一家眼库在角膜组织采集、储存和使用方面面临的挑战和趋势。

材料和方法

分析 1999 年 11 月至 2015 年 10 月间与印度北部一家三级医院相关联的眼库过去的记录,内容包括每年的眼捐献数量、供体人口统计学特征以及角膜组织的使用情况。

结果

前 6 年的捐献数量为 100 例,接下来的 5 年为 279 例,最后 5 年为 473 例。供体的平均年龄为 63.2±19.5 岁。30 岁以下、31-60 岁和 60 岁以上的供体比例分别为 10%、28%和 62%。42%的捐献来自医院。死亡和眼球摘除之间的平均时间为 4.74±5.31 小时。30 岁以下、31-60 岁和 60 岁以上供体年龄组的角膜使用率分别为 61.9%、61.6%和 53.8%。来自家庭和医院的角膜可用性分别为 63.7%和 55.3%。

结论

眼库在开始时反应冷淡,但随着时间的推移逐渐活跃。在我们的社会中普遍存在的神话和信仰阻碍了人们自由捐献眼睛。每个眼库都需要个性化地解决其自身的问题,并找到充分获取和利用组织的解决方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c599/8087588/9b571f1904b6/10792_2021_1736_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c599/8087588/e20505672278/10792_2021_1736_Fig1_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c599/8087588/5b09d875f650/10792_2021_1736_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c599/8087588/9b571f1904b6/10792_2021_1736_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c599/8087588/e20505672278/10792_2021_1736_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c599/8087588/19c9f770f6c6/10792_2021_1736_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c599/8087588/f471691e01a8/10792_2021_1736_Fig3_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c599/8087588/0fc2c5454fd1/10792_2021_1736_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c599/8087588/5b09d875f650/10792_2021_1736_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c599/8087588/9b571f1904b6/10792_2021_1736_Fig7_HTML.jpg

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