Guyer D E, Foale R A, Gillam L D, Wilkins G T, Guerrero J L, Weyman A E
J Am Coll Cardiol. 1986 Oct;8(4):830-5. doi: 10.1016/s0735-1097(86)80424-7.
A convenient noninvasive method of mapping the left ventricular endocardial surface has been developed that can be used to display regional dysfunction and calculate the total area of abnormal endocardial excursion from data obtained in two orthogonal apical and three or more short-axis cross-sectional echocardiographic images. Visually identified regions of abnormal systolic function are plotted on end-diastolic, planar endocardial surface maps, and the extent of dysfunction can be expressed either as an absolute area or as a fraction of the total endocardial surface area involved. The extent of the left ventricular surface moving abnormally, calculated with this echocardiographic mapping technique, was compared with two histochemical measures of infarct size in a series of 11 closed chest dogs with acute circumflex coronary artery occlusions. Overall extent of abnormally moving left ventricular wall correlated closely with both the fraction of the endocardial area overlying infarct (r = 0.92, p less than or equal to 0.001) and the fraction of the myocardial volume infarcted (r = 0.86, p less than or equal to 0.001). This suggests that the echocardiographic mapping technique can be used to accurately quantify the global extent of abnormal systolic function in the presence of regional wall motion abnormalities.
一种便捷的无创性左心室心内膜表面测绘方法已经研发出来，该方法可用于显示局部功能障碍，并根据从两个正交心尖和三个或更多短轴横截面超声心动图图像中获取的数据，计算心内膜异常偏移的总面积。在舒张末期的心内膜平面表面图上绘制视觉识别出的收缩功能异常区域，功能障碍的程度可以用绝对面积表示，也可以用受累的心内膜总面积的分数表示。在一系列11只急性回旋支冠状动脉闭塞的闭胸犬中，将用这种超声心动图测绘技术计算出的左心室表面异常移动的程度，与两种梗死面积的组织化学测量方法进行了比较。左心室壁异常移动的总体程度与覆盖梗死区的心内膜面积分数（r = 0.92，p≤0.001）和梗死心肌体积分数（r = 0.86，p≤0.001）密切相关。这表明，在存在局部壁运动异常的情况下，超声心动图测绘技术可用于准确量化收缩功能异常的整体程度。
