Hajek André, Grupp Katharina, Aarabi Ghazal, Kretzler Benedikt, König Hans-Helmut
Department of Health Economics and Health Services Research, University Medical-Center Hamburg-Eppendorf, Hamburg, Germany.
Division of Plastic, Reconstructive and Aesthetic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Neuropsychiatr Dis Treat. 2023 Aug 16;19:1791-1798. doi: 10.2147/NDT.S412366. eCollection 2023.
To analyze the link between Parkinson's disease and perceived prospects for the future.
Data were taken from the German Ageing Survey (year 2021; n=4296 individuals, thereof 33 individuals with Parkinson's disease) were used. This is a nationally representative sample of community-dwelling individuals ≥ 40 years in Germany. Perceived prospects for the future in different life domains (ie, living standard, health and general optimism) were used as outcomes. Physician-diagnosed Parkinson's disease served as key independent variable . It was adjusted for several covariates.
Individuals with Parkinson's disease had a markedly worse (Cohen's d=0.65) general optimism compared to individuals without Parkinson's disease. After adjusting for various factors, these differences disappeared in multiple linear regressions (β=-0.04, p=0.72). Moreover, multiple ordered logistic regressions showed that individuals with Parkinson's disease had a worse future self-rated health (OR: 4.10, 95% CI: 1.99-8.47, p<0.001) compared to individuals without Parkinson's disease.
Our study first showed that general optimism may be lower among individuals with Parkinson's disease (bivariate analysis). However, this association disappeared when it was adjusted for health-related factors in regression analysis. In sum, our findings indicate that more general future-related factors did not significantly differ between individuals with and without Parkinson's disease. However, there were significant differences in future self-rated health.
分析帕金森病与对未来的感知前景之间的联系。
数据取自德国老龄化调查（2021年；n = 4296人，其中33人患有帕金森病）。这是德国≥40岁社区居住个体的全国代表性样本。将不同生活领域（即生活水平、健康状况和总体乐观程度）的未来感知前景作为结果变量。医生诊断的帕金森病作为关键自变量，并对多个协变量进行了校正。
与未患帕金森病的个体相比，患帕金森病的个体总体乐观程度明显更低（科恩d值 = 0.65）。在对各种因素进行校正后，这些差异在多元线性回归中消失（β = -0.04，p = 0.72）。此外，多元有序逻辑回归显示，与未患帕金森病的个体相比，患帕金森病的个体未来自我评定的健康状况更差（比值比：4.10，95%置信区间：1.99 - 8.47，p < 0.001）。
我们的研究首次表明，帕金森病患者的总体乐观程度可能较低（双变量分析）。然而，在回归分析中对与健康相关的因素进行校正后，这种关联消失了。总之，我们的研究结果表明，患帕金森病和未患帕金森病的个体在更一般的与未来相关的因素方面没有显著差异。然而，在未来自我评定的健康状况方面存在显著差异。
