CAS Key Laboratory of Brain Connectome and Manipulation, Interdisciplinary Center for Brain Information, Chinese Academy of Sciences Shenzhen Institute of Advanced Technology, Shenzhen, China.
International Institute for Brain Research, Qingdao International Academician Park, Qingdao, China.
Mol Pain. 2023 Jan-Dec;19:17448069231197158. doi: 10.1177/17448069231197158.
Music seems promising as an adjuvant pain treatment in humans, while its mechanism remains to be illustrated. In rodent models of chronic pain, few studies reported the analgesic effect of music. Recently, Zhou et al. stated that the analgesic effects of sound depended on a low (5 dB) signal-to-noise ratio (SNR) relative to ambient noise in mice. However, despite employing multiple behavioral analysis approaches, we were unable to extend these findings to a mice model of chronic pain listening to the 5 dB SNR.
音乐似乎很有希望成为人类辅助疼痛治疗的一种方法，但其机制仍有待阐明。在慢性疼痛的啮齿动物模型中，很少有研究报道音乐的镇痛作用。最近，Zhou 等人指出，声音的镇痛效果取决于相对于环境噪声的低（5dB）信噪比（SNR）。然而，尽管我们采用了多种行为分析方法，仍然无法将这些发现扩展到听 5dB SNR 的慢性疼痛小鼠模型中。
