Dizziness Center, Clinical Neuroscience Center, and Department of Neurology, Seoul National University Bundang Hospital, Seongnam, South Korea.
Department of Neurology, Soonchunhyang University College of Medicine, Bucheon, South Korea.
Ann Clin Transl Neurol. 2023 Oct;10(10):1931-1936. doi: 10.1002/acn3.51883. Epub 2023 Aug 21.
Cerebellar nodulus and uvula and their connections with the vestibular nuclei form the so-called velocity-storage circuit. Lesions involving the velocity-storage circuit give rise to positional vertigo and nystagmus. Herein, we present a 32-year-old man with cerebellar nodulus and uvular hemorrhage who showed periodic vertigo and downbeat nystagmus in the supine position. To explain this unusual pattern, we adopted velocity-storage model with a lesion on the neural connection between the gravity and inertia estimators, resulting in periodic neural impulses and a gravity bias in a specific position. This report expands the spectrum of central positional nystagmus due to dysfunction of the velocity-storage mechanism.
小脑小结和小舌及其与前庭核的连接构成了所谓的速度储存回路。涉及速度储存回路的病变会导致位置性眩晕和眼球震颤。本文介绍了一位 32 岁的小脑小结和小舌出血患者，他在仰卧位时表现出周期性眩晕和下跳性眼球震颤。为了解释这种不寻常的模式，我们采用了速度储存模型，病变位于重力和惯性估算器之间的神经连接上，导致周期性的神经冲动和特定位置的重力偏差。本报告扩展了由于速度储存机制功能障碍引起的中枢位置性眼球震颤的谱。
