Hornbruch A, Wolpert L
J Embryol Exp Morphol. 1986 Jun;94:257-65.
Hensen's node from stage 4 to stage 10 shows polarizing activity when grafted to the anterior margin of the chick limb bud. It can specify additional digits though its action is somewhat attenuated when compared with the effect of a grafted polarizing region. At stage 10 the activity disappears from the node and is found both posterior to the node and in the future wing region of the flank. The ability of Hensen's node to generate a positional signal suggests that the signal in the limb and early embryo may be similar. The results support the view of the polarizing region as a discrete signalling region.
从第4阶段到第10阶段的亨氏结移植到鸡胚肢芽前缘时表现出极化活性。它可以指定额外的指（趾），尽管与移植的极化区域的作用相比，其作用有所减弱。在第10阶段，该活性从结中消失，并在结后方和侧翼的未来翅区中被发现。亨氏结产生位置信号的能力表明肢体和早期胚胎中的信号可能相似。这些结果支持将极化区域视为一个离散信号区域的观点。
